College of Bioscience and Biotechnology, Chubu University, Kasugai, Aichi, Japan.
Mol Nutr Food Res. 2012 Jan;56(1):159-70. doi: 10.1002/mnfr.201100526. Epub 2011 Nov 21.
Anthocyanins are one type of flavonoid phytopigment. Although the role of anthocyanins as a functional food factor remains relatively less established than that of other flavonoids, progress in this area has been made at the molecular level in recent years. This review discusses the potential health benefits of plant-derived anthocyanin-rich foods, with a focus on the role of anthocyanins in obesity control, diabetes control, cardiovascular disease prevention, and improvement of visual and brain functions, areas that have attracted much attention. Such health benefits are not necessarily derived from the antioxidant effect of anthocyanins, but in fact are produced by currently unestablished chemical properties beyond the antioxidant capacity of the molecules. However, a better understanding of the physiological functionality of anthocyanins remains to be elucidated. It is desirable, therefore, to clarify the molecular type and composition of the anthocyanins that confer specific health benefits and to conduct further investigation into the underlying molecular mechanisms. The pharmacological actions of anthocyanins could not be fully established without knowledge on the effects of treatment of anthocyanins alone, the effects of non-anthocyanin components, and the possible interactions between anthocyanin and non-anthocyanin species.
花色苷是类黄酮植物色素的一种。虽然花色苷作为功能性食品因子的作用相对于其他类黄酮而言,其研究基础相对薄弱,但近年来在分子水平上,这方面已经取得了一些进展。本综述讨论了植物来源的富含花色苷的食物对健康的潜在益处,重点介绍了花色苷在控制肥胖、控制糖尿病、预防心血管疾病以及改善视觉和大脑功能方面的作用,这些领域引起了广泛关注。这些健康益处不一定来自花色苷的抗氧化作用,而是实际上是由目前尚未确定的、超越分子抗氧化能力的化学性质产生的。然而,花色苷的生理功能仍有待进一步阐明。因此,阐明赋予特定健康益处的花色苷的分子类型和组成,并进一步研究其潜在的分子机制是非常有必要的。如果不了解花色苷单独处理的效果、非花色苷成分的效果以及花色苷和非花色苷物种之间可能存在的相互作用,花色苷的药理作用就无法完全确定。