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基因本体论:2011 年的增强。

The Gene Ontology: enhancements for 2011.

出版信息

Nucleic Acids Res. 2012 Jan;40(Database issue):D559-64. doi: 10.1093/nar/gkr1028. Epub 2011 Nov 18.

Abstract

The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene products has increased due to curation efforts among GO Consortium (GOC) groups, including focused literature-based annotation and ortholog-based functional inference. The GO ontologies continue to expand and improve as a result of targeted ontology development, including the introduction of computable logical definitions and development of new tools for the streamlined addition of terms to the ontology. The GOC continues to support its user community through the use of e-mail lists, social media and web-based resources.

摘要

基因本体论(GO)(http://www.geneontology.org)是一个社区生物信息学资源,通过使用结构化、受控词汇来表示基因产物的功能。由于 GO 联盟(GOC)小组的精心整理工作,包括基于文献的重点注释和基于同源物的功能推断,基因产物的 GO 注释数量有所增加。GO 本体论通过有针对性的本体论开发不断扩展和改进,包括引入可计算的逻辑定义和开发新工具,以简化术语添加到本体论中。GOC 通过使用电子邮件列表、社交媒体和基于网络的资源继续支持其用户社区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56f3/3245151/c9266ef9eed9/gkr1028f1.jpg

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