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2008年的基因本体论项目。

The Gene Ontology project in 2008.

出版信息

Nucleic Acids Res. 2008 Jan;36(Database issue):D440-4. doi: 10.1093/nar/gkm883. Epub 2007 Nov 4.

DOI:10.1093/nar/gkm883
PMID:17984083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2238979/
Abstract

The Gene Ontology (GO) project (http://www.geneontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://www.sequenceontology.org/). The ontologies have been extended and refined for several biological areas, and improvements to the structure of the ontologies have been implemented. To improve the quantity and quality of gene product annotations available from its public repository, the GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of 'reference' genomes, including human and several key model organisms. Software developments include two releases of the ontology-editing tool OBO-Edit, and improvements to the AmiGO browser interface.

摘要

基因本体论（GO）项目（http://www.geneontology.org/）提供了一组结构化的、受控的词汇表，供社区用于注释基因、基因产物和序列（另见http://www.sequenceontology.org/）。这些本体论已针对多个生物学领域进行了扩展和完善，并且对本体论的结构进行了改进。为了提高其公共知识库中可用的基因产物注释的数量和质量，GO联盟已开展重点工作，以对包括人类和几种关键模式生物在内的多个“参考”基因组中的直系同源基因进行全面而详细的注释。软件开发包括本体编辑工具OBO-Edit的两个版本发布，以及对AmiGO浏览器界面的改进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a044/2238979/5e4ae8234d72/gkm883f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a044/2238979/5e4ae8234d72/gkm883f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a044/2238979/5e4ae8234d72/gkm883f1.jpg

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