支柱文章：干扰素α/β信号通路中的一种蛋白酪氨酸激酶。《细胞》。1992年。第70卷：313 - 322页。 - Suppr

Suppr

超能文献

Pillars article: A protein tyrosine kinase in the interferon α/β signaling pathway. Cell. 1992. 70: 313-322.

作者信息

Velazquez Laura, Fellous Marc, Stark George R, Pellegrini Sandra

出版信息

J Immunol. 2011 Dec 1;187(11):5479-88.

PMID:22102731

Abstract

摘要

相似文献

Pillars article: A protein tyrosine kinase in the interferon α/β signaling pathway. Cell. 1992. 70: 313-322.

J Immunol. 2011 Dec 1;187(11):5479-88.

Cytokine signaling: birth of a pathway.

J Immunol. 2011 Dec 1;187(11):5475-8. doi: 10.4049/jimmunol.1102913.

Interferon research BC (before cloning).

Curr Top Microbiol Immunol. 2007;316:9-22. doi: 10.1007/978-3-540-71329-6_2.

Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid.

J Pharmacol Exp Ther. 2007 Feb;320(2):782-9. doi: 10.1124/jpet.106.112052. Epub 2006 Nov 15.

Activity of hybrid type I interferons in cells lacking Tyk2: a common region of IFN-alpha 8 induces a response, but IFN-alpha2/8 hybrids can behave like IFN-beta.

J Interferon Cytokine Res. 2003 Nov;23(11):655-66. doi: 10.1089/107999003322558791.

The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.

Oncogene. 1999 Oct 14;18(42):5727-37. doi: 10.1038/sj.onc.1202960.

The Atlantic salmon protein tyrosine kinase Tyk2: molecular cloning, modulation of expression and function.

Dev Comp Immunol. 2013 Dec;41(4):553-63. doi: 10.1016/j.dci.2013.07.008. Epub 2013 Jul 18.

A mutant form of p135tyk2, an interferon-alpha inducible tyrosine kinase, suppresses the transformed phenotype of Daudi cells.

Leukemia. 1996 Mar;10(3):543-51.

Tyk2 tyrosine kinase expression is required for the maintenance of mitochondrial respiration in primary pro-B lymphocytes.

Mol Cell Biol. 2006 Nov;26(22):8562-71. doi: 10.1128/MCB.00497-06. Epub 2006 Sep 18.

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.

Nature. 1993 Nov 11;366(6451):166-70. doi: 10.1038/366166a0.

引用本文的文献

Hyperimmunoglobulin syndromes: A review of HIGM, HIES, and HIDS.

J Transl Autoimmun. 2025 Jun 27;11:100297. doi: 10.1016/j.jtauto.2025.100297. eCollection 2025 Dec.

A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8991-6. doi: 10.1073/pnas.160130297.

The intracellular domain of interferon-alpha receptor 2c (IFN-alphaR2c) chain is responsible for Stat activation.

Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5007-12. doi: 10.1073/pnas.96.9.5007.

Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex.

Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):915-20. doi: 10.1073/pnas.96.3.915.

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor.

Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11839-44. doi: 10.1073/pnas.94.22.11839.

Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1.

Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8563-8. doi: 10.1073/pnas.94.16.8563.

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals.

Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6910-5. doi: 10.1073/pnas.94.13.6910.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验