Park Young Woo, Koh Eun Jeong, Choi Ha Young
Department of Neurosurgery, Clinical Research Institute, Chonbuk National University Medical School Hospital, Jeonju, Korea.
J Korean Neurosurg Soc. 2011 Sep;50(3):271-3. doi: 10.3340/jkns.2011.50.3.271. Epub 2011 Sep 30.
Juvenile xanthogranuloma (JXG) is an uncommon histiocytic cutaneous lesion. An 18-month-old girl visited our clinic due to rapid growing orange-yellowish lesion on scalp. Enlarging time from 1 mm to 12 mm was just 8 weeks. We excised the tumor and adjacent normal tissue. Histopathological study showed numerous eosinophils and Touton giant cells within the lesion. Immunohistochemical study revealed positive immunoreactivity for CD68 in most areas. No recurrence was seen during 12 months after resection. We report a case with rapidly growing JXG on scalp with peculiar histopathologic findings.
幼年性黄色肉芽肿(JXG)是一种罕见的组织细胞性皮肤病变。一名18个月大的女孩因头皮上迅速生长的橙黄色病变前来我院就诊。病变从1毫米增大到12毫米仅用了8周时间。我们切除了肿瘤及相邻的正常组织。组织病理学研究显示病变内有大量嗜酸性粒细胞和 Touton 巨细胞。免疫组织化学研究显示大部分区域CD68免疫反应呈阳性。切除后12个月内未见复发。我们报告一例头皮上迅速生长的JXG病例,伴有特殊的组织病理学表现。