Swigar M E, Clemow L P, Saidi P, Kim H C
Department of Psychiatry, University of Medicine and Dentistry, Robert Wood Johnson Medical School, New Brunswick, NJ 08903-0019.
Gen Hosp Psychiatry. 1990 Sep;12(5):309-12. doi: 10.1016/0163-8343(90)90048-h.
For the attention of psychiatric consultants, brodifacoum, a new longer-acting, warfarin-like oral anticoagulant rodenticide, has been used for suicide attempts. The overdose potential with brodifacoum is serious since it is readily available without prescription, and bleeding complications last for weeks to months after a single ingestion. This article reports a case of ingestion and reviews four similar cases from medical literature. Also reviewed are details about mechanism of action, procedures for diagnosis, and treatment requirements. Also, characteristics of persons who ingest long-acting anticoagulants appear to differ from those who ingest short-acting anticoagulants reported from earlier literature.
供精神科顾问注意，溴敌隆是一种新型长效、类似华法林的口服抗凝血灭鼠剂，已被用于自杀未遂。溴敌隆的过量服用风险严重，因为无需处方即可轻易获得，且单次摄入后出血并发症可持续数周甚至数月。本文报告了一例摄入溴敌隆的病例，并回顾了医学文献中的四个类似病例。同时还回顾了作用机制、诊断程序和治疗要求的细节。此外，摄入长效抗凝血剂的人群特征似乎与早期文献报道的摄入短效抗凝血剂的人群不同。
