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散发性甲状腺髓样癌的视盘和脉络膜转移:病例报告及文献复习

Optic disc and choroidal metastasis from sporadic medullary thyroid carcinoma: case report and review of the literature.

作者信息

Yildiz Ibrahim, Sen Fatma, Tuncer Samuray, Kilic Leyla, Basaran Mert, Bavbek Sevil

机构信息

Department of Medical Oncology, Istanbul University, Turkey.

出版信息

Onkologie. 2011;34(11):630-3. doi: 10.1159/000334197. Epub 2011 Oct 28.

DOI:10.1159/000334197
PMID:22104161
Abstract

BACKGROUND

Choroidal metastasis is a very rare clinical manifestation of thyroid cancer. Herein, we report on a patient with non-familial medullary thyroid carcinoma (MTC), who presented with choroidal metastasis.

CASE REPORT

A 63-year-old male patient with MTC presented with sudden loss of vision in his right eye for 1 month. The patient had a history of complete thyroidectomy and chemotherapy for disseminated MTC. Ophthalmological examination showed optic disc and choroidal metastases in the right eye and a small choroidal metastasis in the left eye. The patient was scheduled for external irradiation therapy for the ocular area but died 2 months after choroidal metastasis was diagnosed.

CONCLUSIONS

Choroidal metastasis must be considered in MTC patients who develop loss of vision. This is a very rare clinical situation that generally occurs in the late advanced stages of the disease and carries a poor prognosis for these patients.

摘要

背景

脉络膜转移是甲状腺癌一种非常罕见的临床表现。在此,我们报告一例非家族性甲状腺髓样癌(MTC)患者出现脉络膜转移的情况。

病例报告

一名63岁男性MTC患者,右眼突发视力丧失1个月。该患者有因播散性MTC行甲状腺全切术及化疗史。眼科检查显示右眼视盘和脉络膜转移,左眼有一小处脉络膜转移。该患者计划接受眼部区域的外照射治疗,但在脉络膜转移诊断后2个月死亡。

结论

对于出现视力丧失的MTC患者,必须考虑脉络膜转移。这是一种非常罕见的临床情况,通常发生在疾病的晚期,这些患者预后较差。

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Optic disc and choroidal metastasis from sporadic medullary thyroid carcinoma: case report and review of the literature.散发性甲状腺髓样癌的视盘和脉络膜转移:病例报告及文献复习
Onkologie. 2011;34(11):630-3. doi: 10.1159/000334197. Epub 2011 Oct 28.
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Optic disc metastasis presenting as an initial sign of non-small-cell lung cancer: a case report.以视盘转移作为非小细胞肺癌首发症状:一例报告
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