Yildiz Ibrahim, Sen Fatma, Tuncer Samuray, Kilic Leyla, Basaran Mert, Bavbek Sevil
Department of Medical Oncology, Istanbul University, Turkey.
Onkologie. 2011;34(11):630-3. doi: 10.1159/000334197. Epub 2011 Oct 28.
Choroidal metastasis is a very rare clinical manifestation of thyroid cancer. Herein, we report on a patient with non-familial medullary thyroid carcinoma (MTC), who presented with choroidal metastasis.
A 63-year-old male patient with MTC presented with sudden loss of vision in his right eye for 1 month. The patient had a history of complete thyroidectomy and chemotherapy for disseminated MTC. Ophthalmological examination showed optic disc and choroidal metastases in the right eye and a small choroidal metastasis in the left eye. The patient was scheduled for external irradiation therapy for the ocular area but died 2 months after choroidal metastasis was diagnosed.
Choroidal metastasis must be considered in MTC patients who develop loss of vision. This is a very rare clinical situation that generally occurs in the late advanced stages of the disease and carries a poor prognosis for these patients.
脉络膜转移是甲状腺癌一种非常罕见的临床表现。在此,我们报告一例非家族性甲状腺髓样癌(MTC)患者出现脉络膜转移的情况。
一名63岁男性MTC患者,右眼突发视力丧失1个月。该患者有因播散性MTC行甲状腺全切术及化疗史。眼科检查显示右眼视盘和脉络膜转移,左眼有一小处脉络膜转移。该患者计划接受眼部区域的外照射治疗,但在脉络膜转移诊断后2个月死亡。
对于出现视力丧失的MTC患者,必须考虑脉络膜转移。这是一种非常罕见的临床情况,通常发生在疾病的晚期,这些患者预后较差。