神经体液刺激。
Neurohumoral stimulation.
机构信息
Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, 985850 Nebraska Medical Center, Omaha, NE 68198-5850, USA.
出版信息
Heart Fail Clin. 2012 Jan;8(1):87-99. doi: 10.1016/j.hfc.2011.08.007.
Abstract
The temporal relationship between the development of heart failure and activation of the neurohumoral systems involved in chronic heart failure (CHF) has not been precisely defined. When a compensatory mechanism switches to a deleterious contributing factor in the progression of the disease is unclear. This article addresses these issues through evaluating the contribution of various cardiovascular reflexes and cellular mechanisms to the sympathoexcitation in CHF. It also sheds light on some of the important central mechanisms that contribute to the increase in sympathetic nerve activity in CHF.
摘要
心力衰竭的发生与涉及慢性心力衰竭（CHF）的神经体液系统的激活之间的时间关系尚未精确界定。当代偿机制转变为疾病进展中的有害因素时，情况尚不清楚。本文通过评估各种心血管反射和细胞机制对 CHF 中交感神经兴奋的贡献来解决这些问题。它还阐明了一些有助于增加 CHF 中交感神经活动的重要中枢机制。
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