Section of Geriatric Medicine, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
PLoS One. 2011;6(11):e26951. doi: 10.1371/journal.pone.0026951. Epub 2011 Nov 14.
To study the prevalence of eighteen geriatric conditions in older patients at admission, their reporting rate in discharge summaries and the impact of these conditions on mortality and functional decline one year after admission.
A prospective multicenter cohort study conducted between 2006 and 2008 in two tertiary university teaching hospitals and one regional teaching hospital in the Netherlands. Patients of 65 years and older, acutely admitted and hospitalized for at least 48 hours, were invited to participate. Eighteen geriatric conditions were assessed at hospital admission, and outcomes (mortality, functional decline) were assessed one year after admission.
639 patients were included, with a mean age of 78 years. IADL impairment (83%), polypharmacy (61%), mobility difficulty (59%), high levels of primary caregiver burden (53%), and malnutrition (52%) were most prevalent. Except for polypharmacy and cognitive impairment, the reporting rate of the geriatric conditions in discharge summaries was less than 50%. One year after admission, 35% had died and 33% suffered from functional decline. A high Charlson comorbidity index score, presence of malnutrition, high fall risk, presence of delirium and premorbid IADL impairment were associated with mortality and overall poor outcome (mortality or functional decline). Obesity lowered the risk for mortality.
Geriatric conditions were highly prevalent and associated with poor health outcomes after admission. Early recognition of these conditions in acutely hospitalized older patients and improving the handover to the general practitioner could lead to better health outcomes and reduce the burden of hospital admission for older patients.
研究目的在于调查入院老年患者中 18 种老年病的流行率、出院小结中的报告率,以及这些疾病对患者入院 1 年后死亡率和功能衰退的影响。
本研究为前瞻性多中心队列研究,于 2006 年至 2008 年在荷兰的两家三级大学教学医院和一家区域教学医院进行。研究纳入年龄在 65 岁及以上、急性入院且住院时间至少 48 小时的患者。在入院时评估 18 种老年病,入院 1 年后评估结局(死亡率、功能衰退)。
共纳入 639 例患者,平均年龄为 78 岁。最常见的是日常生活活动能力受损(83%)、多重用药(61%)、行动困难(59%)、主要照顾者负担过重(53%)和营养不良(52%)。除多重用药和认知障碍外,出院小结中报告的老年病发生率低于 50%。入院 1 年后,35%的患者死亡,33%的患者功能衰退。Charlson 合并症指数评分高、存在营养不良、高跌倒风险、出现谵妄和病前日常生活活动能力受损与死亡率和整体不良结局(死亡或功能衰退)相关。肥胖降低了死亡率风险。
老年病在入院后老年患者中普遍存在,并与健康结局不良相关。早期识别急性住院老年患者的这些疾病,并改善向全科医生的交接,可能会改善健康结局,减轻老年患者的住院负担。