Pryor Landon S, Gage Earl, Langevin Claude-Jean, Herrera Fernando, Breithaupt Andrew D, Gordon Chad R, Afifi Ahmed M, Zins James E, Meltzer Hal, Gosman Amanda, Cohen Steve R, Holmes Ralph
Craniomaxillofac Trauma Reconstr. 2009 Oct;2(3):151-60. doi: 10.1055/s-0029-1224777.
Bone substitutes are being increasingly used in craniofacial surgery and craniomaxillofacial trauma. We will review the history of the biomaterials and describe the ideal characteristics of bone substitutes, with a specific emphasis on craniofacial reconstruction. Some of the most commonly used bone substitutes are discussed in more depth, such as calcium phosphate and hydroxyapatite ceramics and cements, bioactive glass, and polymer products. Areas of active research and future directions include tissue engineering, with an increasing emphasis on bioactivity of the implant.
骨替代物在颅面外科手术和颅颌面创伤中越来越多地被使用。我们将回顾生物材料的历史，并描述骨替代物的理想特性，特别强调颅面重建。一些最常用的骨替代物将被更深入地讨论，如磷酸钙和羟基磷灰石陶瓷及骨水泥、生物活性玻璃和聚合物产品。活跃的研究领域和未来方向包括组织工程，且越来越强调植入物的生物活性。
