Johnson J H, Tymiak A A, Bolgar M S
Squibb Institute for Medical Research, Princeton, NJ 08543-4000.
J Antibiot (Tokyo). 1990 Aug;43(8):920-30. doi: 10.7164/antibiotics.43.920.
The structures of janthinocins A, B and C, three novel macrocyclic peptide lactone antibiotics isolated from fermentations of Janthinobacterium lividum, were determined. The janthinocins are of particular interest because they contain three amino acid residues that have not previously been reported in natural products: Each contains erythro-beta-hydroxy-D-leucine while janthinocins A and B also contain beta-hydroxytryptophan and beta-ketotryptophan, respectively.
从青紫色杆菌发酵液中分离出的三种新型大环肽内酯抗生素——紫菌素A、B和C的结构已被确定。紫菌素特别引人关注，因为它们含有三种以前在天然产物中未被报道过的氨基酸残基：每种都含有赤藓糖型-β-羟基-D-亮氨酸，而紫菌素A和B还分别含有β-羟基色氨酸和β-酮色氨酸。
