Ellison J M, Milofsky J E, Ely E
Department of Psychiatry, Cambridge Hospital, MA 02139.
J Clin Psychiatry. 1990 Sep;51(9):385-6.
Fluoxetine appears to cause a low incidence of adverse cardiac effects. An uncommon but potentially hazardous effect of fluoxetine therapy, however, is bradycardia accompanied by faintness or syncope. The authors report two cases in which this adverse effect occurred. They hypothesize that the mechanism of bradycardia in these cases represents a direct central nervous system effect of increased serotonin on medullary cardiovascular regulation.
氟西汀似乎会引起不良心脏效应的发生率较低。然而，氟西汀治疗一种罕见但潜在危险的效应是心动过缓并伴有头晕或晕厥。作者报告了两例出现这种不良反应的病例。他们推测，这些病例中心动过缓的机制代表了血清素增加对延髓心血管调节的直接中枢神经系统效应。
