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小核糖核酸病毒,是最常见的呼吸道病毒,可引起各年龄段因急性呼吸道疾病住院患者的感染。

Picornavirus, the most common respiratory virus causing infection among patients of all ages hospitalized with acute respiratory illness.

机构信息

Viral Respiratory Pathogens Research Unit and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.

出版信息

J Clin Microbiol. 2012 Feb;50(2):506-8. doi: 10.1128/JCM.05999-11. Epub 2011 Nov 23.

DOI:10.1128/JCM.05999-11
PMID:22116142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3264172/
Abstract

We evaluated the prevalence of respiratory virus infection (RVI) in 403 illnesses of 364 persons hospitalized over a 2-year period with acute respiratory conditions using virus-specific reverse transcription-PCR (RT-PCR) assays in addition to cell culture and serology. RVIs were identified in >75% of children under 5 years of age and 25 to 37% of adults. The molecular assays doubled the number of infections identified; picornaviruses were the most frequent in patients of all ages, followed by respiratory syncytial virus and influenza viruses.

摘要

我们使用病毒特异性逆转录聚合酶链反应(RT-PCR)检测法,对 364 名患有急性呼吸道疾病住院患者的 403 例疾病进行检测,以评估呼吸道病毒感染(RVI)的流行情况,此外还进行了细胞培养和血清学检测。在 5 岁以下的儿童中,超过 75%的人以及 25 岁至 37%的成年人患有 RVI。分子检测法使感染数量增加了一倍;在所有年龄段的患者中,肠道病毒最为常见,其次是呼吸道合胞病毒和流感病毒。

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