Institute of Environmental Science and Research Limited, Christchurch, New Zealand.
J Clin Microbiol. 2012 Feb;50(2):457-9. doi: 10.1128/JCM.05928-11. Epub 2011 Nov 23.
Pulsed-field gel electrophoresis (PFGE) analysis demonstrated that while 76% of patients had only one genotype of campylobacter, 10% carried two different but related genotypes (Dice coefficients > 0.78), and 14% carried at least two unrelated genotypes (Dice coefficients < 0.65). This supports the clustering of Campylobacter isolates with similar PFGE patterns, highlights the need to analyze multiple isolates from both sources and patients, and confirms that caution should be exercised before epidemiological links between patients or sources are dismissed.
脉冲场凝胶电泳（PFGE）分析表明，虽然 76%的患者只有一种空肠弯曲菌基因型，但 10%的患者携带两种不同但相关的基因型（Dice 系数>0.78），14%的患者携带至少两种不相关的基因型（Dice 系数<0.65）。这支持了具有相似 PFGE 模式的弯曲菌分离株的聚类，突出了需要分析来自两个来源和患者的多个分离株的必要性，并证实了在排除患者或来源之间的流行病学联系之前应谨慎行事。
