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腹腔镜单部位(LESS)胃带术的初步学习经验:寻找成功的预测因素。

Initial learning experience of laparoendoscopic single site (LESS) gastric banding: finding predictors of success.

机构信息

Metropolitan Group Hospitals, University of Illinois at Chicago, Chicago, IL 60657, USA.

出版信息

Obes Surg. 2012 Mar;22(3):433-6. doi: 10.1007/s11695-011-0552-5.

Abstract

Single-incision laparoscopic adjustable gastric banding (SI-LAGB) is a promising technique with potential to decrease pain and improve cosmesis. It is challenging and potentially time-consuming. We aimed to identify preoperative patient characteristics predictive of a successful SI-LAGB. Demographic and anthropometric data were prospectively collected. Primary endpoint was operating time. Adequate operating time (AOT) was determined using a historic consecutive of 100 subjects undergoing multi-port LAGB. The cutoff for AOT was defined as mean + 1 SD of the historic cohort. Binary logistic regression analysis was used in univariate and multivariate modeling to identify independent preoperative variables associated with AOT. From February 2009 to October 2010, 79 patients (71 female) underwent SI-LAGB, with no conversions to multi-port laparoscopy. Mean operating time was 61 ± 27 min. The cohort was divided into two groups: AOT (n = 53) and excessive operating time, (EOT, n = 26) based on cutoff value of 69 min. On univariate analysis, preoperative BMI had significant (p = 0.03) counterintuitive effect on operative time (AOT 44.2 ± 6.2 kg/m(2) versus EOT 42.1 ± 4.2 kg/m(2)). Hiatal hernia was also significant predictor of EOT (19.2% versus 3.7%; p = 0.001) and remained an independent predictor of EOT in multivariate logistic regression after adjusting for covariates, increasing the chance for EOT by 5.9 times (odd ratio 5.9; 95% CI 1.1-31.1; p = 0.04). SI-LAGB can be performed safely and timely. Concomitant hiatal hernia could be successfully repaired during a SI-LAGB but at the cost of significant additional operating time.

摘要

单切口腹腔镜可调胃束带术(SI-LAGB)是一种有前途的技术,具有减轻疼痛和改善美容效果的潜力。但它具有挑战性,并且潜在地耗时。我们旨在确定预测 SI-LAGB 成功的术前患者特征。前瞻性收集了人口统计学和人体测量学数据。主要终点是手术时间。使用接受多端口 LAGB 的 100 例连续患者的历史记录确定了足够的手术时间(AOT)。AOT 的截止值定义为历史队列的均值+1 SD。使用单变量和多变量建模中的二元逻辑回归分析来确定与 AOT 相关的独立术前变量。从 2009 年 2 月至 2010 年 10 月,79 例患者(71 例女性)接受了 SI-LAGB 治疗,无转为多孔腹腔镜手术。平均手术时间为 61±27 分钟。根据 69 分钟的截止值,将队列分为两组:AOT(n=53)和手术时间过长组(EOT,n=26)。在单变量分析中,术前 BMI 对手术时间有明显的(p=0.03)反直觉影响(AOT 44.2±6.2kg/m2与 EOT 42.1±4.2kg/m2)。食管裂孔疝也是 EOT 的显著预测因子(19.2%与 3.7%;p=0.001),并且在调整协变量后,在多变量逻辑回归中仍然是 EOT 的独立预测因子,使 EOT 的机会增加 5.9 倍(比值比 5.9;95%可信区间 1.1-31.1;p=0.04)。SI-LAGB 可以安全且及时地进行。同时可以成功修复食管裂孔疝,但代价是显著增加手术时间。

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