非高密度脂蛋白胆固醇及其与血液透析患者心血管风险人体测量标志物的相关性。
Non-high-density lipoprotein cholesterol and its correlation with anthropometric markers of cardiovascular risk in hemodialysis.
机构信息
Department of Internal Medicine, Faculty of Medicine Christus, Fortaleza, Ceara, Brazil; Department of Nephrology, Federal University of Ceara, Fortaleza, Ceara, Brazil.
Graduation of Faculty of Medicine Christus, Fortaleza, Ceara, Brazil.
出版信息
J Ren Nutr. 2012 Mar;22(2):251-257. doi: 10.1053/j.jrn.2011.08.009. Epub 2011 Nov 25.
INTRODUCTION
Non-high-density lipoprotein cholesterol (non-HDL-c) may be a better indicator of atherogenicity in the hemodialysis population.
PURPOSE
To investigate the correlation of non-HDL-c with anthropometric measurements associated to cardiovascular risk, such as body mass index, waist circumference, waist-to-height ratio, waist-to-height(2) ratio, and waist-to-hip circumference ratio.
METHODS
We evaluated anthropometric markers and lipids in 86 hemodialysis patients, and the correlation between them was investigated.
RESULTS
Non-HDL-c had a positive correlation with body mass index (r = 0.273; P = .01), waist circumference (r = 0.375; P = .000), waist-to-height ratio (r = 0.333; P = .002), waist-to-height(2) ratio (r = 0.270; P = .012), and waist-to-hip circumference ratio (r = 0.356; P = .001).
CONCLUSIONS
This study detected a positive and significant correlation between non-HDL-c, but not low-density lipoprotein cholesterol, and the anthropometric cardiovascular risk indexes. We could suggest that non-HDL-c can be used as a cardiovascular risk factor indicator among dialysis patients.
简介
非高密度脂蛋白胆固醇（non-HDL-c）可能是血液透析人群致动脉粥样硬化的更好指标。
目的
研究非高密度脂蛋白胆固醇与心血管风险相关的人体测量指标（如体重指数、腰围、腰高比、腰高比(2)和腰臀比）之间的相关性。
方法
我们评估了 86 名血液透析患者的人体测量标志物和血脂，并研究了它们之间的相关性。
结果
非高密度脂蛋白胆固醇与体重指数（r = 0.273；P =.01）、腰围（r = 0.375；P =.000）、腰高比（r = 0.333；P =.002）、腰高比(2)（r = 0.270；P =.012）和腰臀比（r = 0.356；P =.001）呈正相关。
结论
本研究发现非高密度脂蛋白胆固醇与心血管风险的人体测量指标之间存在正相关且有统计学意义，但与低密度脂蛋白胆固醇无关。我们可以推测，非高密度脂蛋白胆固醇可作为透析患者心血管风险因素的指标。
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