Suppr超能文献

SAPHIR 研究中的身体肥胖指数和其他身体成分指标:与心血管危险因素的关联。

Body adiposity index and other indexes of body composition in the SAPHIR study: association with cardiovascular risk factors.

机构信息

Department of Internal Medicine I, Innsbruck Medical University, Innsbruck, Austria.

出版信息

Obesity (Silver Spring). 2013 Apr;21(4):775-81. doi: 10.1002/oby.20289.

Abstract

OBJECTIVE

The accuracy of anthropometric surrogate markers such as the body adiposity index (BAI) and other common indexes like the body mass index (BMI), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) to predict metabolic sequelae is essential for its use in clinical practice.

DESIGN AND METHODS

Thus, we evaluated the strength of BAI and other indexes to relate with anthropometric parameters, adipocytokines, blood lipids, parameters of glucose-homeostasis and blood pressure in 1,770 patients from the Salzburg Atherosclerosis Prevention Program in Subjects at High Individual Risk (SAPHIR) study in a crosssectional design. Measurements were BAI, BMI, WHR, WHtR, abdominal subcutaneous and visceral adipose tissue (aSAT and VAT), total body adipose tissue mass, body weight, waist- and hip circumference (WC and HC), leptin, adiponectin, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides (TG), fasting plasma glucose, fasting plasma insulin, the homeostasis model assessment of insulin resistance (HOMAIR), systolic and diastolic blood pressure.

RESULTS AND CONCLUSIONS

BAI was significantly associated with leptin and HC. We conclude that BAI was the best calculator for leptin. BAI was inferior to BMI to predict anthropometric parameters other than HC, adiponectin, blood lipids, parameters of glucose homeostasis, and blood pressure in this cross-sectional study.

摘要

目的

人体脂肪指数(BAI)等人体肥胖替代指标以及体重指数(BMI)、腰臀比(WHR)和腰高比(WHtR)等其他常见指标,对于预测代谢后果具有很高的准确性,因此,对于其在临床实践中的应用至关重要。

设计和方法

因此,我们在横断面研究中评估了 BAI 和其他指标与人体测量参数、脂肪细胞因子、血脂、血糖稳态参数和血压之间的相关性,该研究纳入了来自萨尔茨堡高个体风险动脉粥样硬化预防计划中的 1770 名受试者(SAPHIR 研究)。测量指标包括 BAI、BMI、WHR、WHtR、腹部皮下和内脏脂肪组织(aSAT 和 VAT)、全身脂肪组织质量、体重、腰围和臀围(WC 和 HC)、瘦素、脂联素、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、空腹血糖、空腹胰岛素、胰岛素抵抗的稳态模型评估(HOMAIR)、收缩压和舒张压。

结果和结论

BAI 与瘦素和 HC 显著相关。我们得出结论,BAI 是计算瘦素的最佳指标。在这项横断面研究中,BAI 预测除 HC、脂联素、血脂、血糖稳态参数和血压以外的人体测量参数的能力逊于 BMI。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验