Department of Internal Medicine I, Innsbruck Medical University, Innsbruck, Austria.
Obesity (Silver Spring). 2013 Apr;21(4):775-81. doi: 10.1002/oby.20289.
The accuracy of anthropometric surrogate markers such as the body adiposity index (BAI) and other common indexes like the body mass index (BMI), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) to predict metabolic sequelae is essential for its use in clinical practice.
Thus, we evaluated the strength of BAI and other indexes to relate with anthropometric parameters, adipocytokines, blood lipids, parameters of glucose-homeostasis and blood pressure in 1,770 patients from the Salzburg Atherosclerosis Prevention Program in Subjects at High Individual Risk (SAPHIR) study in a crosssectional design. Measurements were BAI, BMI, WHR, WHtR, abdominal subcutaneous and visceral adipose tissue (aSAT and VAT), total body adipose tissue mass, body weight, waist- and hip circumference (WC and HC), leptin, adiponectin, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides (TG), fasting plasma glucose, fasting plasma insulin, the homeostasis model assessment of insulin resistance (HOMAIR), systolic and diastolic blood pressure.
BAI was significantly associated with leptin and HC. We conclude that BAI was the best calculator for leptin. BAI was inferior to BMI to predict anthropometric parameters other than HC, adiponectin, blood lipids, parameters of glucose homeostasis, and blood pressure in this cross-sectional study.
人体脂肪指数(BAI)等人体肥胖替代指标以及体重指数(BMI)、腰臀比(WHR)和腰高比(WHtR)等其他常见指标,对于预测代谢后果具有很高的准确性,因此,对于其在临床实践中的应用至关重要。
因此,我们在横断面研究中评估了 BAI 和其他指标与人体测量参数、脂肪细胞因子、血脂、血糖稳态参数和血压之间的相关性,该研究纳入了来自萨尔茨堡高个体风险动脉粥样硬化预防计划中的 1770 名受试者(SAPHIR 研究)。测量指标包括 BAI、BMI、WHR、WHtR、腹部皮下和内脏脂肪组织(aSAT 和 VAT)、全身脂肪组织质量、体重、腰围和臀围(WC 和 HC)、瘦素、脂联素、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、空腹血糖、空腹胰岛素、胰岛素抵抗的稳态模型评估(HOMAIR)、收缩压和舒张压。
BAI 与瘦素和 HC 显著相关。我们得出结论,BAI 是计算瘦素的最佳指标。在这项横断面研究中,BAI 预测除 HC、脂联素、血脂、血糖稳态参数和血压以外的人体测量参数的能力逊于 BMI。