一种身体形状指数与传统人体测量参数用于识别围绝经期/绝经后女性的亚临床动脉粥样硬化

A Body Shape Index versus Traditional Anthropometric Parameters to Identify Subclinical Atherosclerosis in Perimenopausal/Menopausal Women.

作者信息

Nimkuntod Porntip, Tongdee Pattama

出版信息

J Med Assoc Thai. 2016 Oct;99 Suppl 7:S81-6.

PMID:29901934

Abstract

BACKGROUND

The body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR) are well-used anthropometric predictors for cardiovascular diseases (CVD), but their validity is regularly questioned. Recently, A body shape index (ABSI) was introduced as an alternative anthropometric index that may better reflect health status.

OBJECTIVE

To assess the ability of ABSI to identify a marker of early atherosclerosis using carotid intima media thickness (CIMT) and determine whether it is superior to traditional anthropometrics: BMI, WC, and WHR.

MATERIAL AND METHOD

This is a cross-sectional study of 114 participants, aged 40 to 80 years, recruited from the cardiovascular clinic and menopausal clinic between February 2015 and January 2016. CIMTs were measured using B-mode ultrasonography. The novel ABSI, both ABSI [American (A) and Asian or Indonesia formula (I)] and traditional anthropometric parameters (BMI, WC, and WHR) were measured. Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDLC), and low-density lipoprotein cholesterol (LDL-C) were assessed in the entire population.

RESULTS

There was 114 participants with mean age of 53.75±9.92 years and mean CIMT of 0.70±0.15 mm. The prevalence of abnormal CIMT was 22.3%. ABSI (A), ABSI (I), and BMI were significantly different between normal and atherosclerotic CIMT ≥0.9 mm (p<0.001). Both ABSI (A) and ABSI (I) were correlated with atherosclerosis (r = 0.211, p = 0.024), (r = 0.188, p = 0.046) but there was no correlation with mean CIMT. The anthropometric parameters WC and WHR were correlated with mean CIMT, however they had no correlation with atherosclerosis. Only the traditional anthropometrics BMI was not correlated with CIMT or atherosclerosis.

CONCLUSION

ABSI (A) and ABSI (I) could predict the presence of early atherosclerosis but have no correlation with mean CIMT, as opposed to the anthropometric indices WC and WHR.

摘要

背景

体重指数（BMI）、腰围（WC）和腰臀比（WHR）是常用于预测心血管疾病（CVD）的人体测量指标，但其有效性常受到质疑。最近，一种体型指数（ABSI）被引入，作为一种可能能更好反映健康状况的替代人体测量指标。

目的

评估ABSI利用颈动脉内膜中层厚度（CIMT）识别早期动脉粥样硬化标志物的能力，并确定其是否优于传统人体测量指标：BMI、WC和WHR。

材料与方法

这是一项横断面研究，于2015年2月至2016年1月从心血管诊所和更年期诊所招募了114名年龄在40至80岁之间的参与者。使用B型超声测量CIMT。测量了新型ABSI，包括ABSI[美国（A）版和亚洲或印度尼西亚公式（I）版]以及传统人体测量参数（BMI、WC和WHR）。对整个人群评估了总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDLC）和低密度脂蛋白胆固醇（LDL-C）。

结果

共有114名参与者，平均年龄为53.75±9.92岁，平均CIMT为0.70±0.15mm。CIMT异常的患病率为22.3%。正常与动脉粥样硬化CIMT≥0.9mm之间，ABSI（A）、ABSI（I）和BMI存在显著差异（p<0.001）。ABSI（A）和ABSI（I）均与动脉粥样硬化相关（r = 0.211，p = 0.024），（r = 0.188，p = 0.046），但与平均CIMT无相关性。人体测量参数WC和WHR与平均CIMT相关，然而它们与动脉粥样硬化无相关性。只有传统人体测量指标BMI与CIMT或动脉粥样硬化无相关性。