Edo A, Adediran O S
Departments of Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.
West Afr J Med. 2011 May-Jun;30(3):206-9.
Nigerians working in the oil industry appear to maintain a 'westernised' lifestyle and thus may be at increased risk for diabetes mellitus and related disorders. There are several reports on lipid profile in type 2 DM among Nigerians (non-oil workers) in the general population from different parts of the country. However the lipid profile of Nigerian oil workers with type 2 DM has not been previously reported.
To determine the serum lipid profile of Nigerian oil workers with or without type 2 diabetes mellitus.
Hospital records of Nigerian oil workers with type 2 diabetes mellitus were retrieved for the study. Data extracted included the patient's age, sex, weight, height, waist circumference, blood pressure and fasting lipid profile. Hospital staff without DM served as controls.
There were 52 Nigerians with type 2 DM and 99 controls. Serum triglyceride levels were significantly higher in diabetics than in controls (1.91±1.10 vs 1.27 ±0.58mmol/l, p<0.001). The other lipid fractions were comparable in both diabetics and non-diabetics. High-density lipoprotein cholesterol abnormality was found in 32.7% of diabetic subjects. Serum total cholesterol dyslipidaemia, triglyceride dsylipidaemia and low-density lipoprotein cholesterol dyslipidaemia were found in 26.9%, 19.2% and 9.6% of the diabetic subjects respectively.
Dyslipidaemia in Nigerian oil workers with T2DM is common and consists mainly of hypertriglycendaemic and low HDL cholesterol. Measures should be instituted to reduce the lipid levels in these patients in order to minimize the risk of cardiovascular events.
在石油行业工作的尼日利亚人似乎保持着“西方化”的生活方式，因此患糖尿病及相关疾病的风险可能会增加。关于该国不同地区普通人群中尼日利亚人（非石油行业工作者）2型糖尿病患者的血脂谱已有多篇报道。然而，此前尚未报道过患有2型糖尿病的尼日利亚石油行业工作者的血脂谱情况。
确定患有或未患有2型糖尿病的尼日利亚石油行业工作者的血清血脂谱。
检索尼日利亚石油行业2型糖尿病工作者的医院记录用于本研究。提取的数据包括患者的年龄、性别、体重、身高、腰围、血压和空腹血脂谱。无糖尿病的医院工作人员作为对照。
有52名患有2型糖尿病的尼日利亚人和99名对照者。糖尿病患者的血清甘油三酯水平显著高于对照组（1.91±1.10 vs 1.27±0.58mmol/l，p<0.001）。其他血脂成分在糖尿病患者和非糖尿病患者中相当。32.7%的糖尿病患者存在高密度脂蛋白胆固醇异常。分别有26.9%、19.2%和9.6%的糖尿病患者存在血清总胆固醇血脂异常、甘油三酯血脂异常和低密度脂蛋白胆固醇血脂异常。
患有2型糖尿病的尼日利亚石油行业工作者血脂异常情况常见，主要表现为高甘油三酯血症和低高密度脂蛋白胆固醇血症。应采取措施降低这些患者的血脂水平，以将心血管事件风险降至最低。
