Vesterbro-Enghave Psykiatrisk Center, Hvidovre Hospital Department of Psychiatry, Copenhagen, Denmark.
Int J Psychiatry Clin Pract. 2011 Sep;15(3):219-27. doi: 10.3109/13651501.2011.582538. Epub 2011 Jun 27.
We evaluated the hypotheses that A Quick Test of Cognitive Speed (AQT) single- and dual-dimension naming speed measures would differentiate normal adults and adults with ADHD before medication and that there would be no differences between groups after stabilization with medication.
Thirty adults with ADHD, aged 18-43, were evaluated with the AQT color (C), form (F) and color-form combination (CF) naming tests before and after medication with methylphenidate. Thirty age- and sex-matched normal adults served as controls.
Among adults with ADHD, pre-medication naming times (s) for C, F, and CF were significantly longer and overhead [CF - (C + F)] significantly larger than post-medication. Before medication, C, F and CF naming and processing efficiency (overhead) (s) differed significantly between ADHD adults and controls. After medication, there were no significant differences between groups. When we used fail criteria for dual-dimension naming (> 60 s) and overhead (processing efficiency) (> + 6 s) together the sensitivity was 93% and specificity 100%.
Within the study limitations, findings suggest that the processing-speed and efficiency measures in AQT may be used to screen adults for executive dysfunction and reduced cognitive control associated with ADHD.
我们评估了以下两个假设：AQT 的单项和双项命名速度测试能够区分未用药的 ADHD 成年患者和正常成年人，以及在药物稳定后，两组之间不会存在差异。
30 名年龄在 18-43 岁的 ADHD 成年患者在服用哌甲酯前后分别接受 AQT 的颜色（C）、形状（F）和颜色-形状组合（CF）命名测试。30 名年龄和性别匹配的正常成年人作为对照组。
在 ADHD 成年患者中，用药前的 C、F 和 CF 命名时间显著延长，而 CF 减去（C+F）的开销显著增大。在用药前，ADHD 成年患者和对照组在 C、F 和 CF 命名以及处理效率（开销）方面存在显著差异。在用药后，两组之间没有显著差异。当我们同时使用双项命名（>60 秒）和开销（处理效率）（>6 秒）的失败标准时，敏感性为 93%，特异性为 100%。
在研究限制范围内，结果表明 AQT 的加工速度和效率测量可能用于筛选与 ADHD 相关的执行功能障碍和认知控制能力下降的成年人。
