Aliautdin R N, Buianov V V, Lemina E Iu, Muratov V K, Samoĭlov D N
Farmakol Toksikol. 1979 May-Jun;42(3):239-43.
Tests on cats showed the compound RGH 1106 to possess an antidepolarizing mechanism of action. The sequence of myorelaxation, arising under the effect of this agent, is characterized by relaxation in the first place of the musculus masseter, muscles of limbs, then of abdominal muscles and those of the diaphragm and, finally, of the intercostal muscles. RGH 1106 doses not possess cardiotropic m-cholinolytic action, does not exert a ganglion blocking effect, nor affects the central nervous system. It neither changes the blood supply of the myocardium and the uptake of oxygen by the latter, nor inhibits the acetylcholinesterase.
对猫的测试表明，化合物RGH 1106具有抗去极化作用机制。在该药物作用下产生的肌肉松弛顺序的特征是，首先是咬肌、四肢肌肉松弛，然后是腹肌、膈肌松弛，最后是肋间肌松弛。RGH 1106没有强心性M-胆碱能作用，不产生神经节阻断作用，也不影响中枢神经系统。它既不改变心肌的血液供应和心肌对氧的摄取，也不抑制乙酰胆碱酯酶。
