Food for Health Ireland, Moorepark Food Research Center, Fermoy, County Cork, Ireland.
Annu Rev Food Sci Technol. 2011;2:299-329. doi: 10.1146/annurev-food-022510-133721.
There is an increased desire for sophisticated foods, whereby consumers harbor higher expectations of health-promoting benefits above basic nutrition. Moreover, there is a move from the adulteration of foods with chemical preservatives toward biopreservation. Such expectations have led scientists to identify novel approaches to satisfy both demands, which utilize bacteriocin and peptide-based solutions. The best known examples of biopreservation involve bacteriocins. However, with the exception of nisin, bacteriocins have received limited use in the food industry. Peptides can be added to foods to improve consumer health. Some of the best known examples are angiotensin I-converting enzyme (ACE)-inhibitory peptides, which inhibit ACE, a key enzyme involved in blood pressure (BP) regulation. To be effective, these peptides must be bioavailable, but by their nature, peptides are degraded by digestion with proteolytic enzymes. This review critically discusses the use and potential of peptides and bacteriocins in food systems in terms of safety, quality, and improvement of human health.
人们对精致食品的需求日益增长,消费者对食品的期望不仅停留在提供基本营养,还希望其具有促进健康的功效。此外,食品添加剂正从化学防腐剂向生物防腐剂转变。这种期望促使科学家们寻找新的方法来满足这两方面的需求,即利用细菌素和肽类物质来解决问题。生物防腐剂的最佳例子就是细菌素。然而,除了乳链菌肽之外,细菌素在食品工业中的应用非常有限。人们可以在食物中添加肽类物质来改善消费者的健康。其中最著名的例子是血管紧张素转化酶(ACE)抑制肽,它可以抑制 ACE,ACE 是一种参与血压调节的关键酶。为了达到效果,这些肽类物质必须是生物可利用的,但由于其性质,肽类物质会在消化过程中被蛋白水解酶降解。本文从安全性、质量和人类健康改善等方面,批判性地讨论了肽类物质和细菌素在食品系统中的应用和潜力。