载铁蛋白- CeO2 纳米松露，具有优异的人工氧化还原酶活性。
Apoferritin-CeO2 nano-truffle that has excellent artificial redox enzyme activity.
机构信息
Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
出版信息
Chem Commun (Camb). 2012 Mar 28;48(26):3155-7. doi: 10.1039/c1cc15815e. Epub 2011 Dec 1.
PMID:22129765
Abstract
4.5 nm nanoceria particles are successfully encapsulated into the apoferritin cavity via a dissociation-reconstruction route. The apoferritin coating not only improves the biocompatibility and changes the cellular uptake route of nanoceria, but also manipulates the electron localization at the surface of the nanoparticle thereby ameliorating the ROS-scavenging activity.
摘要
4.5nm 纳米氧化铈颗粒成功地通过解组装-再组装途径被包裹到脱铁铁蛋白空腔中。脱铁铁蛋白的包覆不仅提高了纳米氧化铈的生物相容性并改变了其细胞摄取途径，而且还能调控纳米颗粒表面的电子局域化，从而改善其 ROS 清除活性。
Zotero 插件