Audebert A, Darai E, Bénifla J-L, Yazbeck C, Déchaud H, Wattiez A, Crowe A, Pouly J-L
Service d'endoscopie gynécologique, polyclinique de Bordeaux, 145, rue du Tondu, 33000 Bordeaux, France.
Gynecol Obstet Fertil. 2012 Jun;40(6):365-70. doi: 10.1016/j.gyobfe.2011.10.002. Epub 2011 Nov 29.
Adhesions are the most frequent complications of abdominopelvic surgery, causing important short- and long-term problems, including infertility, chronic pelvic pain and a lifetime risk of small bowel obstruction. They also complicate future surgery with increased morbidity and mortality risk. They pose serious quality of life issues for many patients with associated social and healthcare costs. Despite advances in surgical techniques, including laparoscopy, the healthcare burden of adhesion-related complications has not changed in recent years. Adhesiolysis remains the main treatment although adhesions reform in many patients. The extent of the problem of adhesions has been underestimated by surgeons and the health authorities. There is rising evidence however that surgeons can take important steps to reduce the impact of adhesions. As well as improvements in surgical technique, developments in adhesion-reduction strategies and new agents offer a realistic possibility of reducing adhesion formation and improving outcomes for patients. This paper is the first of a two-part publication providing a comprehensive overview of the evidence on adhesions to allow gynaecological surgeons to be best informed on adhesions, their development, impact on patients, health systems and surgical outcomes. In the second paper we review the various strategies to reduce the impact of adhesions and improve surgical outcomes to assist fellow surgeons in France to consider the adoption of adhesion reduction strategies in their own practice.
粘连是腹部盆腔手术最常见的并发症,会引发重要的短期和长期问题,包括不孕、慢性盆腔疼痛以及终身的小肠梗阻风险。它们还会使未来的手术变得复杂,增加发病和死亡风险。它们给许多患者带来严重的生活质量问题,并产生相关的社会和医疗成本。尽管包括腹腔镜手术在内的手术技术有所进步,但近年来粘连相关并发症的医疗负担并未改变。粘连松解术仍然是主要治疗方法,不过许多患者的粘连会复发。粘连问题的严重程度一直被外科医生和卫生当局低估。然而,越来越多的证据表明,外科医生可以采取重要措施来减轻粘连的影响。除了手术技术的改进,减少粘连策略的发展和新药物为减少粘连形成和改善患者预后提供了切实可行的可能性。本文是一篇分两部分发表的文章中的第一篇,全面概述了有关粘连的证据,以使妇科外科医生能够充分了解粘连、其形成、对患者、卫生系统和手术结果的影响。在第二篇文章中,我们将回顾各种减少粘连影响并改善手术结果的策略,以帮助法国的外科同行考虑在自己的实践中采用减少粘连的策略。