真性空卵泡综合征的发生率。
The prevalence of genuine empty follicle syndrome.
机构信息
Eunice Kennedy Shriver National Institute of Child Health and Human Development, Program in Reproductive and Adult Endocrinology, Bethesda, Maryland, USA.
出版信息
Fertil Steril. 2011 Dec;96(6):1375-7. doi: 10.1016/j.fertnstert.2011.09.047.
Abstract
OBJECTIVE
To describe the prevalence of "genuine" empty follicle syndrome (EFS) and "false" EFS at assisted reproductive technology (ART).
DESIGN
Retrospective cohort.
SETTING
Large private fertility center.
PATIENT(S): A total of 12,359 patients who underwent ART between 2004 and 2009.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): The failure to recover an oocyte during oocyte retrieval at ART, with and without a detectable serum β-hCG on the day of retrieval.
RESULT(S): Two cases of genuine EFS and nine cases of false EFS were identified in the cohort examined. The prevalence of genuine EFS was 0.016%, and the prevalence of false EFS was 0.072%. Only two out of 11 cases of EFS were considered genuine.
CONCLUSION(S): Genuine EFS is a rare occurrence. Because this syndrome tends to recur with dismal pregnancy rates at ART, continued identification and further investigation of the syndrome are needed.
摘要
目的
描述辅助生殖技术（ART）中“真性”空卵泡综合征（EFS）和“假性”EFS 的发生率。
设计
回顾性队列研究。
地点
大型私立生育中心。
患者
2004 年至 2009 年间共 12359 名接受 ART 的患者。
干预措施
无。
主要观察指标
ART 取卵时未能回收卵母细胞，以及取卵日血清β-hCG 是否可检测。
结果
在检查的队列中发现了 2 例真性 EFS 和 9 例假性 EFS。真性 EFS 的发生率为 0.016%，假性 EFS 的发生率为 0.072%。EFS 中有 11 例中有 2 例被认为是真性的。
结论
真性 EFS 是一种罕见的情况。由于该综合征在 ART 中再次发生时妊娠率不佳，因此需要继续识别和进一步研究该综合征。
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