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心理肾病学:常染色体显性遗传多囊肾病的心理方面。

Psychonephrology: psychological aspects in autosomal dominant polycystic kidney disease.

机构信息

Nephrology Research Unit. Dr Negrín University Hospital Gran Canaria, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Las Palmas, Spain.

出版信息

Nefrologia. 2011;31(6):716-22. doi: 10.3265/Nefrologia.pre2011.Jul.10847.

DOI:10.3265/Nefrologia.pre2011.Jul.10847
PMID:22130288
Abstract

The biological, physical and psychological burden of a chronic disease has an impact on the quality of life of people who suffer from it. The perception of quality of life is affected by psychological disorders such as anxiety and depression that have a high prevalence in people with chronic kidney disease (CKD). These factors are also linked to lower life expectancy. It is therefore surprising that the psychological aspects of people with autosomal dominant polycystic kidney disease (ADPKD) have received so little attention in the medical literature, despite their importance for the overall health of these patients. The relatively new discipline called psychonephrology provides a broader view of the impact that these aspects have on individuals with chronic kidney disease, with a consequent practical application. In this article, we examine the consequences and prevalence of psychological problems that can be related to CKD and ADPKD. Firstly, we will focus on the field of CKD and ADPKD within the scope of psychonephrology. Secondly, the article introduces the concept of quality of life as a basic pillar of health that is affected when a person is diagnosed with CKD. Thirdly, we will present a summary of the main research related to anxiety and depression disorders in CKD and ADPKD. The article will conclude by synthesising findings from the different lines of research undertaken.

摘要

慢性病的生理、物理和心理负担会影响患者的生活质量。生活质量的认知受到焦虑和抑郁等心理障碍的影响,这些障碍在慢性肾病(CKD)患者中发病率很高。这些因素也与预期寿命降低有关。令人惊讶的是,尽管自身显性多囊肾病(ADPKD)患者的心理方面对于这些患者的整体健康很重要,但在医学文献中却很少关注这些方面。一个名为精神肾病学的相对较新学科提供了一个更广泛的视角,了解这些方面对慢性肾病患者的影响,并随之产生了实际应用。在本文中,我们将研究与 CKD 和 ADPKD 相关的心理问题的后果和流行率。首先,我们将重点关注精神肾病学范围内的 CKD 和 ADPKD 领域。其次,本文介绍了生活质量作为一个人被诊断患有 CKD 时会受到影响的健康基本支柱的概念。第三,我们将总结与 CKD 和 ADPKD 中的焦虑和抑郁障碍相关的主要研究。最后,本文将综合不同研究领域的发现。

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1
Psychonephrology: psychological aspects in autosomal dominant polycystic kidney disease.心理肾病学:常染色体显性遗传多囊肾病的心理方面。
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引用本文的文献

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A Diagnosis or a Trap: Exploring the Psychosocial and Ethical Impacts of Autosomal Dominant Polycystic Kidney Disease Diagnosis.诊断还是陷阱:探索常染色体显性多囊肾病诊断的心理社会和伦理影响
Healthcare (Basel). 2025 Jun 2;13(11):1316. doi: 10.3390/healthcare13111316.
2
The relationship between depression, anxiety, quality of life levels, and the chronic kidney disease stage in the autosomal dominant polycystic kidney disease.常染色体显性多囊肾病中抑郁、焦虑、生活质量水平与慢性肾病分期之间的关系。
Int Urol Nephrol. 2023 Apr;55(4):983-992. doi: 10.1007/s11255-022-03375-2. Epub 2022 Oct 2.
3
A Systematic Review of Reported Outcomes in ADPKD Studies.
常染色体显性多囊肾病(ADPKD)研究中报告结果的系统评价
Kidney Int Rep. 2022 Jul 5;7(9):1964-1979. doi: 10.1016/j.ekir.2022.06.012. eCollection 2022 Sep.
4
Brain dysfunction in tubular and tubulointerstitial kidney diseases.管状和肾小管间质性肾病中的脑功能障碍。
Nephrol Dial Transplant. 2021 Dec 28;37(Suppl 2):ii46-ii55. doi: 10.1093/ndt/gfab276.
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Influence of Depression and Anxiety on Hemodialysis Patients: The Value of Multidisciplinary Care.抑郁和焦虑对血液透析患者的影响:多学科护理的价值。
Int J Environ Res Public Health. 2021 Mar 29;18(7):3544. doi: 10.3390/ijerph18073544.
6
Understanding the physical and emotional impact of early-stage ADPKD: experiences and perspectives of patients and physicians.了解早期常染色体显性多囊肾病的身体和情感影响:患者及医生的经历与观点
Clin Kidney J. 2015 Oct;8(5):531-7. doi: 10.1093/ckj/sfv060. Epub 2015 Jul 28.