Department of Urology, the Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Urology. 2012 Feb;79(2):266-9. doi: 10.1016/j.urology.2011.09.040. Epub 2011 Nov 30.
To perform a study to describe the way in which an increasingly obese body mass index (BMI) is associated with urinary tract infection (UTI). The association between UTI and obesity is not well characterized. In fact, previous investigations of this subject have yielded conflicting findings. UTI is increasingly being recognized as a preventable complication, and UTI rates are used to measure quality of surgical care.
We evaluated claims over a 5-year period (2002-2006) in a national private claims database to identify patients diagnosed with UTI or pyelonephritis by ICD-9 coding. Descriptive analyses were performed and odds ratios were calculated.
A total of 95,598 subjects were identified for evaluation. Gender distribution was 42.9% male and 57.1% female. In the overall study cohort, the diagnosis of a UTI or pyelonephritis occurred in 13% and 0.84%, respectively. Women were 4.2 times more likely to be diagnosed with a UTI (19.3% vs 4.6%), and 3.6 times more likely to be diagnosed with pyelonephritis (1.22% vs 0.34%), than were men. At all stratifications of obesity, the obese were significantly more likely to be diagnosed with a UTI or pyelonephritis than nonobese patients.
Elevated BMI appears to be associated with an increased risk for UTI and pyelonephritis. Further study is needed to determine whether this association may be attributed to a cause-and-effect relationship. However, these results may serve to guide clinicians who treat obese patients, because it may be an additional benefit of weight loss.
进行一项研究，描述不断增加的肥胖身体质量指数（BMI）与尿路感染（UTI）之间的关系。UTI 与肥胖之间的关联尚未得到充分描述。事实上，之前对这一主题的研究得出了相互矛盾的结论。UTI 越来越被认为是一种可预防的并发症，而 UTI 发生率被用来衡量手术护理的质量。
我们评估了在一个全国性私人索赔数据库中进行的为期 5 年（2002-2006 年）的索赔数据，以确定通过 ICD-9 编码诊断为 UTI 或肾盂肾炎的患者。进行了描述性分析并计算了比值比。
共确定了 95598 名患者进行评估。性别分布为男性占 42.9%，女性占 57.1%。在整个研究队列中，分别有 13%和 0.84%的患者被诊断为 UTI 或肾盂肾炎。女性被诊断为 UTI 的可能性是男性的 4.2 倍（19.3%比 4.6%），被诊断为肾盂肾炎的可能性是男性的 3.6 倍（1.22%比 0.34%）。在肥胖的所有分层中，肥胖患者被诊断为 UTI 或肾盂肾炎的可能性明显高于非肥胖患者。
升高的 BMI 似乎与 UTI 和肾盂肾炎的风险增加有关。需要进一步研究以确定这种关联是否可能归因于因果关系。然而，这些结果可能有助于指导治疗肥胖患者的临床医生，因为这可能是减肥的另一个额外益处。
