Horstink M W, Berger H J, van Spaendonck K P, van den Bercken J H, Cools A R
Department of Neurology, University of Nijmegen, The Netherlands.
J Neurol Neurosurg Psychiatry. 1990 Aug;53(8):685-90. doi: 10.1136/jnnp.53.8.685.
The ability to share time and to shift attention between bimanual simultaneous motor tasks were studied in 18 patients with Parkinson's disease (PD) and 19 age- and intelligence-matched controls. The task consisted of drawing triangles with the dominant hand and squeezing a rubber bulb with the nondominant hand. Motor performance was measured using the variables: amplitude of squeezing, frequency of squeezing and velocity of drawing triangles. After eliminating variance due to baseline differences in single-handed performance, the bimanual simultaneous performance of PD and controls turned out to be similar to the frequency of squeezing and the velocity of drawing triangles. The amplitude of squeezing, however, differed between the two groups: it was significantly reduced in PD. Arguably the disturbance in the bimanual performance of PD patients was not due to a disorder of time sharing, but to a decreased ability to shift attention from the visually cued task to the non visually cued task. The results agree with current evidence that PD patients are more impaired when they have to rely upon internal control for the regulation of shifting attention than when external cues are available.
在18名帕金森病（PD）患者和19名年龄及智力匹配的对照组中，研究了在双手同时进行的运动任务之间共享时间和转移注意力的能力。任务包括用优势手画三角形，并用非优势手挤压橡胶球。使用以下变量测量运动表现：挤压幅度、挤压频率和画三角形的速度。在消除因单手表现的基线差异导致的方差后，PD患者和对照组的双手同时表现与挤压频率和画三角形的速度相似。然而，两组之间的挤压幅度有所不同：PD患者的挤压幅度显著降低。可以说，PD患者双手表现的干扰不是由于时间共享障碍，而是由于将注意力从视觉提示任务转移到非视觉提示任务的能力下降。这些结果与当前的证据一致，即与有外部线索时相比，PD患者在必须依靠内部控制来调节注意力转移时受损更严重。
