Ikeguchi Masahide, Kuroda Hirohiko, Kihara Kyouichi, Hatata Tomoko, Matsunaga Tomoyuki, Fukuda Kenji, Saito Hiroaki, Tatebe Shigeru
Department of Surgery, Division of Surgical Oncology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, 683-8504 Japan.
Indian J Surg. 2010 Dec;72(6):453-7. doi: 10.1007/s12262-010-0167-4. Epub 2010 Nov 17.
The aim of this study was to evaluate the nutritional advantages of pylorus-preserving gastrectomy (PPG) in comparison with distal gastrectomy with Billroth I anastomosis (DG) in early gastric cancer (EGC). Between 2005 and 2007, 24 patients underwent PPG and 30 underwent DG. Subjective global assessment, objective data assessment, and endoscopic findings of the remnant stomach were compared between the two groups. Two years after surgery, the patients' body weights recovered to 97% in PPG, but they continued to decrease in DG. Postoperative blood lymphocyte counts remained low in DG, but recovered to preoperative levels 6 months after surgery in PPG. Food residue in the gastric remnant was frequently observed in PPG (71.4%) than in DG (15.8%, P = 0.001). In nutritional aspect, PPG may be a more ideal operation than DG. However, food residue in the gastric remnant should be considered in PPG.
The online version of this article (doi:10.1007/s12262-010-0167-4) contains supplementary material, which is available to authorized users.
本研究的目的是评估早期胃癌(EGC)患者中,保留幽门胃切除术(PPG)相较于毕Ⅰ式远端胃切除术(DG)的营养优势。2005年至2007年期间,24例患者接受了PPG,30例接受了DG。比较了两组患者的主观整体评估、客观数据评估以及残胃的内镜检查结果。术后两年,PPG组患者体重恢复至术前的97%,而DG组患者体重持续下降。DG组术后血淋巴细胞计数持续偏低,而PPG组术后6个月恢复至术前水平。PPG组(71.4%)胃残端食物残留的发生率高于DG组(15.8%,P = 0.001)。在营养方面,PPG可能是比DG更理想的手术方式。然而,PPG应考虑胃残端食物残留的问题。
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