Gros Daniel F, Haren W Blake
Ralph H. Johnson VAMC, Charleston and Medical University of South Carolina, Charleston, South Carolina, USA.
Prim Care Companion CNS Disord. 2011;13(4). doi: 10.4088/PCC.11m01136.
Major depressive disorder (MDD) is highly prevalent and impairing and highly likely to present in primary care settings. Recent efforts by the Department of Veterans Affairs (VA) have sought to integrate mental health services into primary care settings, leading to new specialty pharmacotherapy and psychotherapy treatment options for primary care patients. However, little is known about the effectiveness of these new services in primary care patients with MDD. The present study investigated the effectiveness of a brief, easy-to-administer, evidence-based psychotherapy behavioral activation in an integrated mental health/primary care setting in a southeastern VA medical center during the first year of the program.
Thirty-five veterans with MDD (DSM-IV criteria) completed an initial clinical intake, were given the Mini International Neuropsychiatric Interview, and began a 4-week behavioral activation program. Patients also completed the Hospital Anxiety and Depression Scale (HADS) at intake, posttreatment, and at 1-month follow-up. The study was conducted from November 2009 to November 2010.
Sixty percent (n = 21) of patients completed the brief behavioral activation. Treatment completers demonstrated significant reductions in symptoms of both anxiety and depression on the HADS at posttreatment (t values > 5.2, P values < .001, d values > 1.16, g values > 1.02) and follow-up (t values > 4.0, P values < .01, d values > 1.74, g values > 1.67) when compared to pretreatment levels.
The present findings support the use of behavioral activation as an effective treatment for patients with MDD in a primary care setting. These findings suggest that new integrated primary care settings should incorporate behavioral activation to offer brief, evidence-based treatments that provide reliable symptom reductions in addition to possible reductions in treatment needs and better management of related physical health conditions.
重度抑郁症(MDD)极为常见且具有损害性,在初级保健机构中很可能出现。美国退伍军人事务部(VA)近期致力于将心理健康服务纳入初级保健机构,为初级保健患者带来了新的专科药物治疗和心理治疗选择。然而,对于这些新服务在患有MDD的初级保健患者中的有效性知之甚少。本研究调查了在东南部VA医疗中心的心理健康/初级保健综合环境中,一种简短、易于实施且基于证据的心理治疗——行为激活疗法在该项目第一年的有效性。
35名符合MDD(DSM-IV标准)的退伍军人完成了初始临床接诊,接受了迷你国际神经精神访谈,并开始了为期4周的行为激活项目。患者在接诊时、治疗后以及1个月随访时还完成了医院焦虑抑郁量表(HADS)。该研究于2009年11月至2010年11月进行。
60%(n = 21)的患者完成了简短的行为激活治疗。与治疗前水平相比,完成治疗的患者在治疗后(t值> 5.2,P值< .001,d值> 1.16,g值> 1.02)和随访时(t值> 4.0,P值< .01,d值> 1.74,g值> 1.67)的HADS焦虑和抑郁症状均显著减轻。
本研究结果支持在初级保健环境中使用行为激活疗法治疗MDD患者。这些发现表明,新的综合初级保健机构应纳入行为激活疗法,以提供简短、基于证据的治疗,除了可能减少治疗需求和更好地管理相关身体健康状况外,还能可靠地减轻症状。