Bascom Palmer Eye Institute, University of Miami School of Medicine, 900 North West 17th Street, Miami, FL 33136, USA.
Lasers Med Sci. 2013 Feb;28(2):683-92. doi: 10.1007/s10103-011-1021-z. Epub 2011 Dec 2.
Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as maintaining visual acuity. Trials have stressed the importance of early identification and treatment of threshold and high-risk prethreshold disease to improve outcomes. Retinal ablation with laser photocoagulation should involve entire treatment of avascular retina with a confluent laser spot density, avoiding skip lesions. The current review highlights the use of laser photocoagulation in the treatment of ROP.
视网膜发育涉及一系列复杂的事件协调,这些事件可能会受到早产的影响,导致早产儿视网膜病变(ROP),这是一种潜在的致盲性儿童疾病。无血管的视网膜会导致疾病进一步恶化,激光光凝术可以降低不利的解剖学结果,并维持视力。试验强调了早期识别和治疗阈值和高危阈前病变以改善结局的重要性。视网膜激光光凝术应包括对无血管视网膜进行完全治疗,采用融合的激光光斑密度,避免遗漏病变。本综述重点介绍了激光光凝术在 ROP 治疗中的应用。