Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway.
Schizophr Res. 2012 Mar;135(1-3):79-83. doi: 10.1016/j.schres.2011.11.015. Epub 2011 Dec 3.
Neurocognitive deficits and self-disorders (i.e. altered basic self-awareness or - sense of self) have both been suggested as fundamental trait features of schizophrenia. However, no study until now has investigated the relationship between these two core features.
To investigate the relationship between self-disorders and neurocognitive performance in patients with schizophrenia.
Self-disorders were assessed in 57 patients in the early phase of schizophrenia by means of the Examination of Anomalous Self-Experience (EASE) instrument. The neurocognitive assessments included measures of psychomotor speed, working memory, executive- and memory functions.
There were few associations between self-disorders and neurocognitive impairments. However, high levels of SDs were significantly associated with impaired verbal memory.
The reason for the general lack of associations between self-disorders and neurocognition could be that they represent different basic features of the illness. Verbal memory may however be linked to deficits in the patients' ability to comprehend, direct, remember and reason about their thoughts, functions that are intimately related to the basic sense of self.
神经认知缺陷和自我障碍（即基本自我意识或自我意识改变）都被认为是精神分裂症的基本特征。然而，到目前为止，还没有研究调查这两个核心特征之间的关系。
探讨精神分裂症患者自我障碍与神经认知功能的关系。
采用异常自我体验检查（EASE）量表对 57 例精神分裂症早期患者进行自我障碍评估。神经认知评估包括精神运动速度、工作记忆、执行和记忆功能的测量。
自我障碍与神经认知障碍之间的相关性较小。然而，高水平的 SDs 与言语记忆受损显著相关。
自我障碍与神经认知之间普遍缺乏关联的原因可能是它们代表了疾病的不同基本特征。然而，言语记忆可能与患者理解、指导、记忆和推理自己的思想的能力缺陷有关，这些功能与基本的自我意识密切相关。
