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欧洲精神病学协会(EPA)关于自杀治疗和预防的指南。

The European Psychiatric Association (EPA) guidance on suicide treatment and prevention.

机构信息

The National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.

出版信息

Eur Psychiatry. 2012 Feb;27(2):129-41. doi: 10.1016/j.eurpsy.2011.06.003. Epub 2011 Dec 1.

Abstract

UNLABELLED

Suicide is a major public health problem in the WHO European Region accounting for over 150,000 deaths per year. SUICIDAL CRISIS: Acute intervention should start immediately in order to keep the patient alive.

DIAGNOSIS

An underlying psychiatric disorder is present in up to 90% of people who completed suicide. Comorbidity with depression, anxiety, substance abuse and personality disorders is high. In order to achieve successful prevention of suicidality, adequate diagnostic procedures and appropriate treatment for the underlying disorder are essential.

TREATMENT

Existing evidence supports the efficacy of pharmacological treatment and cognitive behavioural therapy (CBT) in preventing suicidal behaviour. Some other psychological treatments are promising, but the supporting evidence is currently insufficient. Studies show that antidepressant treatment decreases the risk for suicidality among depressed patients. However, the risk of suicidal behaviour in depressed patients treated with antidepressants exists during the first 10-14 days of treatment, which requires careful monitoring. Short-term supplementary medication with anxiolytics and hypnotics in the case of anxiety and insomnia is recommended. Treatment with antidepressants of children and adolescents should only be given under supervision of a specialist. Long-term treatment with lithium has been shown to be effective in preventing both suicide and attempted suicide in patients with unipolar and bipolar depression. Treatment with clozapine is effective in reducing suicidal behaviour in patients with schizophrenia. Other atypical antipsychotics are promising but more evidence is required. TREATMENT TEAM: Multidisciplinary treatment teams including psychiatrist and other professionals such as psychologist, social worker, and occupational therapist are always preferable, as integration of pharmacological, psychological and social rehabilitation is recommended especially for patients with chronic suicidality. FAMILY: The suicidal person independently of age should always be motivated to involve family in the treatment. SOCIAL SUPPORT: Psychosocial treatment and support is recommended, as the majority of suicidal patients have problems with relationships, work, school and lack functioning social networks.

SAFETY

A secure home, public and hospital environment, without access to suicidal means is a necessary strategy in suicide prevention. Each treatment option, prescription of medication and discharge of the patient from hospital should be carefully evaluated against the involved risks. TRAINING OF PERSONNEL: Training of general practitioners (GPs) is effective in the prevention of suicide. It improves treatment of depression and anxiety, quality of the provided care and attitudes towards suicide. Continuous training including discussions about ethical and legal issues is necessary for psychiatrists and other mental health professionals.

摘要

未注明

自杀是世卫组织欧洲区域的一个主要公共卫生问题,每年有超过 15 万人因此死亡。自杀危机:应立即开始进行急性干预,以确保患者的生命安全。

诊断

在 90%以上自杀身亡的人中,都存在潜在的精神疾病。同时存在抑郁、焦虑、物质滥用和人格障碍等合并症的比例很高。为了成功预防自杀倾向,必须进行充分的诊断程序并对潜在疾病进行适当的治疗。

治疗

现有证据支持药物治疗和认知行为疗法(CBT)在预防自杀行为方面的有效性。其他一些心理治疗方法也很有希望,但目前证据不足。研究表明,抗抑郁治疗可以降低抑郁患者自杀的风险。然而,在接受抗抑郁药物治疗的抑郁患者中,在治疗的头 10-14 天存在自杀行为的风险,这需要仔细监测。在焦虑和失眠的情况下,建议短期补充抗焦虑药和催眠药。儿童和青少年的抗抑郁药物治疗应在专家监督下进行。锂的长期治疗已被证明可有效预防单相和双相抑郁症患者的自杀和自杀未遂。氯氮平治疗可有效减少精神分裂症患者的自杀行为。其他非典型抗精神病药物也很有前途,但需要更多的证据。治疗团队:包括精神科医生和其他专业人员(如心理学家、社会工作者和职业治疗师)在内的多学科治疗团队总是更好的选择,因为建议整合药物治疗、心理治疗和社会康复,特别是对有慢性自杀倾向的患者。家庭:应始终鼓励有自杀倾向的人,无论年龄大小,让家人参与治疗。社会支持:建议进行心理社会治疗和支持,因为大多数有自杀倾向的患者都存在人际关系、工作、学业和缺乏功能社交网络方面的问题。

安全

在预防自杀方面,一个安全的家庭、公共和医院环境,以及没有自杀手段,是必要的策略。应仔细评估每个治疗选择、药物处方和患者出院的风险。人员培训:对全科医生(GP)进行培训可有效预防自杀。它可以改善对抑郁和焦虑的治疗、提供的护理质量以及对自杀的态度。精神科医生和其他心理健康专业人员需要进行持续培训,包括讨论伦理和法律问题。

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