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新冠疫情期间儿童自杀未遂事件减少:一项欧洲多中心研究。

Pediatric suicide attempts lagged during the COVID-19 pandemic: a European multicenter study.

作者信息

Moscoso Ana, Cousien Anthony, Serra Giulia, Erlangsen Annette, Vila Mar, Paradžik Ljubica, Pires Sandra, Villar Francisco, Bogadi Marija, da Silva Pedro Caldeira, Vicari Stefano, Krantz Mette Falkenberg, Delorme Richard

机构信息

Child and Adolescent Psychiatry Department, Robert Debré Hospital, APHP & Université Paris Cité Paris, 48, Boulevard Sérurier, 75935 Paris Cedex 19, Paris, France.

Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, F‑75018, Paris, France.

出版信息

Child Adolesc Psychiatry Ment Health. 2024 Aug 7;18(1):98. doi: 10.1186/s13034-024-00784-2.

Abstract

BACKGROUND

Elevated rates of suicidal behavior were reported during the COVID-19 pandemic. However, information is scarce on patients' profiles during this period. Studies evoke the potential adverse effects of the mandatory lockdown, but they remain relatively speculative.

METHODS

We monitored fluctuations in suicide attempts (SA) in six European countries. We gathered data, retrospectively for under 18-year-old SA episodes (1 January 2018 to 31 December 2021), through records of psychiatric emergency services. We collected clinical profiles individually. We extracted environmental indicators by month, as provided by Oxford COVID-19 Government Response Tracker (OxCGRT). We used the Pruned Exact Linear Time (PELT) method to identify breakpoints in SA episodes reported for each country, and logistic regressions to estimate changes in patients' characteristics after the breakpoints. Finally, we used a univariate and multivariate negative binomial model to assess the link between SA and OxCGRT indicators, accounting for the delay (lag) between the interventions and their impact on SA.

RESULTS

The study comprised 2,833 children and adolescents (mean age = 15.1 years (SD 1.6); M: F sex-ratio = 1:5.4). A significant increase in SA was found either 6 or 10 months after the beginning of the pandemic, varying by country. Patients were more likely to be girls (aOR = 1.77 [1.34; 2.34]) and used SA methods "other than self-poisoning" (aOR = 1.34 [1.05; 1.7]). In the multivariate model, an association was found between SA and the contact tracing indicator with an 11 months delay, and the number of COVID-19 deaths with a 3-months delay.

CONCLUSIONS

Findings confirmed a delayed increase in SA during the COVID-19 pandemic in children and adolescents as well as changes in patients' profiles. The duration and severity of the pandemic emerged as the strongest predictor in the rise of SA. If faced with a similar pandemic in the future, the gap between the onset of pandemic and the increase in suicide attempts presents an opportunity for prevention.

摘要

背景

在新冠疫情期间,有报告称自杀行为发生率有所上升。然而,关于这一时期患者特征的信息却很匮乏。研究引发了对强制封锁潜在不利影响的探讨,但这些探讨仍相对具有推测性。

方法

我们监测了六个欧洲国家自杀未遂(SA)情况的波动。我们通过精神科急诊服务记录,回顾性收集了18岁以下自杀未遂事件(2018年1月1日至2021年12月31日)的数据。我们分别收集了临床特征。我们按照牛津新冠疫情政府应对追踪器(OxCGRT)提供的信息逐月提取环境指标。我们使用修剪精确线性时间(PELT)方法来确定每个国家报告的自杀未遂事件中的断点,并使用逻辑回归来估计断点后患者特征的变化。最后,我们使用单变量和多变量负二项模型来评估自杀未遂与OxCGRT指标之间的关联,并考虑干预措施与其对自杀未遂影响之间的延迟(滞后)。

结果

该研究纳入了2833名儿童和青少年(平均年龄 = 15.1岁(标准差1.6);男女比例 = 1:5.4)。在疫情开始后的6个月或10个月,不同国家出现了自杀未遂显著增加的情况。患者更有可能是女孩(调整后比值比 = 1.77 [1.34; 2.34]),且使用“非自我中毒”的自杀未遂方法(调整后比值比 = 1.34 [1.05; 1.7])。在多变量模型中,发现自杀未遂与接触者追踪指标之间存在关联,延迟为11个月,与新冠死亡人数之间存在关联,延迟为3个月。

结论

研究结果证实,在新冠疫情期间,儿童和青少年的自杀未遂情况出现了延迟增加,以及患者特征发生了变化。疫情的持续时间和严重程度成为自杀未遂上升的最强预测因素。如果未来面临类似疫情,疫情爆发与自杀未遂增加之间的时间差为预防工作提供了机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5f5/11308394/1239eb09e709/13034_2024_784_Fig1_HTML.jpg

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