预后营养指数可作为结直肠癌的预后指标。
The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma.
机构信息
Department of Surgery, Fukuoka Higashi Medical Center, 1-1-1 Chidori, Koga, Japan.
出版信息
Surg Today. 2012 Jun;42(6):532-5. doi: 10.1007/s00595-011-0061-0. Epub 2011 Dec 3.
PURPOSE
Preoperative assessments regarding a patient's immunological and nutritional condition are required to predict the outcomes of patients with malignant tumors. The aim of the current study was to clarify the significance of Onodera's prognostic nutritional index (OPNI), which can simply account for the immunological and nutritional conditions, in patients with colorectal carcinoma.
METHODS
The correlations of the preoperative OPNI value with clinicopathological features were examined in 219 patients with colorectal carcinoma who had been surgically treated.
RESULTS
Not only the tumor stage (P = 0.028) and venous invasion (P = 0.002), but also an OPNI of less than 40 (P = 0.002) were found to be independently correlated with a worse prognosis of patients with colorectal carcinoma.
CONCLUSION
The preoperative OPNI can be used as a simple prognostic indicator in colorectal carcinoma.
目的
需要对患者的免疫和营养状况进行术前评估，以预测恶性肿瘤患者的预后。本研究的目的是阐明奥野预后营养指数（OPNI）的意义，该指数可以简单地反映免疫和营养状况，在结直肠癌患者中的作用。
方法
对 219 例接受手术治疗的结直肠癌患者的术前 OPNI 值与临床病理特征进行了相关性分析。
结果
不仅肿瘤分期（P=0.028）和静脉侵犯（P=0.002），而且 OPNI 值小于 40（P=0.002）与结直肠癌患者的预后不良也有独立相关性。
结论
术前 OPNI 可作为结直肠癌的一种简单的预后指标。
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