CALIPHO Group, Swiss Institute of Bioinformatics, CMU - 1, Rue Michel Servet 1211 Geneva 4, Switzerland.
Nucleic Acids Res. 2012 Jan;40(Database issue):D76-83. doi: 10.1093/nar/gkr1179. Epub 2011 Dec 1.
neXtProt (http://www.nextprot.org/) is a new human protein-centric knowledge platform. Developed at the Swiss Institute of Bioinformatics (SIB), it aims to help researchers answer questions relevant to human proteins. To achieve this goal, neXtProt is built on a corpus containing both curated knowledge originating from the UniProtKB/Swiss-Prot knowledgebase and carefully selected and filtered high-throughput data pertinent to human proteins. This article presents an overview of the database and the data integration process. We also lay out the key future directions of neXtProt that we consider the necessary steps to make neXtProt the one-stop-shop for all research projects focusing on human proteins.
neXtProt(http://www.nextprot.org/)是一个新的以人类蛋白质为中心的知识平台。它由瑞士生物信息学研究所(SIB)开发,旨在帮助研究人员回答与人类蛋白质相关的问题。为了实现这一目标,neXtProt 建立在一个包含经过精心整理的知识的语料库之上,这些知识源自 UniProtKB/Swiss-Prot 知识库,以及经过精心挑选和过滤的与人类蛋白质相关的高通量数据。本文概述了数据库和数据集成过程。我们还阐述了 neXtProt 的未来主要发展方向,我们认为这些方向是使 neXtProt 成为所有专注于人类蛋白质研究项目的一站式资源的必要步骤。