Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Angew Chem Int Ed Engl. 2011 Dec 23;50(52):12406-10. doi: 10.1002/anie.201106707. Epub 2011 Dec 5.
At warp speed: The speed and cost of sequencing DNA has undergone tremendous improvement based on Solexa sequencing. This technique arose from basic curiosity-driven research and unexpected outcomes, rather than from ideas that were strategically driven. The whole-genome sequencing of individuals now possible may one day transform the way medical disorders are classified, diagnosed, and treated.
基于 Solexa 测序,DNA 测序的速度和成本都有了巨大的提高。这项技术源于基础的好奇心驱动的研究和意外的结果,而不是出于战略驱动的想法。个体的全基因组测序现在已经成为可能,有朝一日可能会改变医学疾病的分类、诊断和治疗方式。