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简短报告:危地马拉基于设施的监测系统对贾第虫、隐孢子虫和土壤传播性蠕虫的分子认识。

Short report: Molecular insights for Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in Guatemala.

机构信息

Center for Global Health, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA.

出版信息

Am J Trop Med Hyg. 2011 Dec;85(6):1141-3. doi: 10.4269/ajtmh.2011.11-0437.

Abstract

We molecularly characterized samples with Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in Santa Rosa, Guatemala. The DNA sequence analysis determined the presence of Giardia assemblages A (N = 7) and B (N = 12) and, Cryptosporidium hominis (N = 2) and Cryptosporidium parvum (N = 2), suggestive of different transmission cycles. All 41 samples with soil-transmitted helminths did not have the β-tubulin mutation described for benzimidazole resistance, suggesting potential usefulness in mass drug administration campaigns.

摘要

我们对来自危地马拉圣罗莎基于设施的腹泻监测系统的样品进行了贾第虫、隐孢子虫和土壤传播性蠕虫的分子特征分析。DNA 序列分析确定了贾第虫 A (N=7)和 B (N=12)组合体以及隐孢子虫人型(N=2)和微小隐孢子虫(N=2)的存在,提示存在不同的传播周期。所有 41 个有土壤传播性蠕虫的样本均未出现描述的苯并咪唑耐药的β-微管蛋白突变,这表明在大规模药物治疗运动中可能具有潜在的用途。

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