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[阵发性室上性折返性心动过速抗心律失常治疗的发病机制方法标准]

[Criteria for a pathogenetic approach to antiarrhythmic therapy in paroxysmal supraventricular reciprocal tachycardia].

作者信息

Chireĭkin L V, Shubik Iu V, Tiunin M I

出版信息

Kardiologiia. 1990 Jun;30(6):55-9.

PMID:2214533
Abstract

An electrophysiological study using programmed transesophageal atrial pacing was performed in 106 patients with abnormalities in the myocardial conduction system, of whom 102 suffered from paroxysmal supraventricular reciprocal tachycardia and/or paroxysmal atrial fibrillation. The electrophysiological properties of the myocardial conduction system were demonstrated to be labile. The factors determining the frequency and length of palpitations were outlined. The conditions for an onset of supraventricular reciprocal tachycardiac paroxysm and for existence of a reentrant chain were found to be minimal in the effective refractory period of the accessory pathway, which was less or equal to the effective refractory period of the atrioventricular junction. An approach to antiarrhythmic therapy was proposed, which was based on modifying the ratio of the effective refractory periods of normal and abnormal excitation pathways.

摘要

对106例心肌传导系统异常的患者进行了经食管程控心房起搏的电生理研究,其中102例患有阵发性室上性折返性心动过速和/或阵发性心房颤动。结果表明,心肌传导系统的电生理特性不稳定。概述了决定心悸频率和持续时间的因素。发现室上性折返性心动过速发作和折返环存在的条件在旁路有效不应期最小,该不应期小于或等于房室交界区的有效不应期。提出了一种抗心律失常治疗方法,该方法基于改变正常和异常兴奋通路有效不应期的比例。

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1
[Criteria for a pathogenetic approach to antiarrhythmic therapy in paroxysmal supraventricular reciprocal tachycardia].[阵发性室上性折返性心动过速抗心律失常治疗的发病机制方法标准]
Kardiologiia. 1990 Jun;30(6):55-9.
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[Serial testing of anti-arrhythmia preparations using the intracardiac electrophysiological study of patients with reciprocal paroxysmal tachycardias].
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