Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia.
Expert Rev Med Devices. 2012 Jan;9(1):33-48. doi: 10.1586/erd.11.58.
The concept of an electronic visual prosthesis has been investigated since the early 20th century. While the first generation of long-term implantable devices were defined by the turn of the millennium, the greatest progress has been achieved in the past decade. This review describes the current state of the art of visual prosthesis investigated by more than two dozen active groups in this field of research. The focus is on technological solutions in regard to long-term safety of materials, electrode-tissue interfaces and encapsulation technologies. Furthermore, we critically assess the maximum number of stimulating electrodes each technological approach is likely to provide.
自 20 世纪初以来,人们一直在研究电子视觉假体的概念。虽然第一代长期可植入设备是在世纪之交定义的,但在过去十年中取得了最大的进展。本综述描述了目前由该研究领域的二十多个活跃研究小组研究的视觉假体的最新技术。重点是关于材料、电极-组织界面和封装技术的长期安全性的技术解决方案。此外,我们还对每种技术方法可能提供的最大刺激电极数量进行了批判性评估。