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泰国药用植物。二: Entada rheedei Sprengel 种仁的化学研究。

Medicinal plants of Thailand. II: chemical studies on the seed kernels of Entada rheedei Sprengel.

机构信息

Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

出版信息

J Nat Med. 2012 Jul;66(3):552-7. doi: 10.1007/s11418-011-0608-9. Epub 2011 Dec 7.

Abstract

Chemical investigation of a methanolic extract of the seed kernels of Entada rheedei (Fabaceae), a Thai medicinal plant taken for stomachache, led to the isolation of five new compounds, 1-(3,4-dimethoxyphenyl)propan-9-ol O-(6″-O-α-L-arabinopyranosyl)-β-D-glucopyranoside, 1-(3,4,5-trimethoxyphenyl)prop-7-en-9-ol O-(6″-O-α-L-arabinopyranosyl)-β-D-glucopyranoside, and N-(2'-hydroxyethyl)-7-phenylacetamide 2'-O-β-D-glucopyranoside, and entadamide A 2'-O-(4″-O-β-D-glucopyranosyl)-β-D-glucopyranoside and 2'-O-(6″-O-β-D-glucopyranosyl)-β-D-glucopyranosides, together with one known compound, corchoionoside C. Their structures were elucidated on the basis of chemical and spectral evidence.

摘要

从泰国药用植物 Entada rheedei(含羞草科)的种仁甲醇提取物中进行化学研究,得到了五个新化合物:1-(3,4-二甲氧基苯基)丙-9-醇 O-(6″-O-α-L-阿拉伯吡喃糖基)-β-D-吡喃葡萄糖苷、1-(3,4,5-三甲氧基苯基)丙-7-烯-9-醇 O-(6″-O-α-L-阿拉伯吡喃糖基)-β-D-吡喃葡萄糖苷、N-(2'-羟基乙基)-7-苯乙酰胺 2'-O-β-D-吡喃葡萄糖苷,以及 entadamide A 2'-O-(4″-O-β-D-吡喃葡萄糖基)-β-D-吡喃葡萄糖苷和 2'-O-(6″-O-β-D-吡喃葡萄糖基)-β-D-吡喃葡萄糖苷,以及一个已知化合物 corchoionoside C。基于化学和光谱证据阐明了它们的结构。

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