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[腺毛黑种草籽化学成分的研究]

[Studies on the chemical constituents of seed from Nigella glandulifera].

作者信息

Hao H F, Ren L J, Chen Y W

机构信息

Department of Meteria Medica and Pharmacology, China-Japan Friendship Hospital, Beijing.

出版信息

Yao Xue Xue Bao. 1996;31(9):689-94.

PMID:9863234
Abstract

Seven compounds were isolated from the seed of Nigella glandulifera. Their structures were identified as kaempferol-3-O-beta-D-galactopyranosyl (1-->3)-beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranoside (N-I), 2-O-[alpha-D-galactopyranosyl (1-->4)-beta-D-glucopyranosyl]-beta-D-fructofuranoside (N-II), N, N-dimethyl-1, 2-dimethoxy-10, 11-dihydric aporphine quaternary ammonium chloride (N-III), 3-O-[beta-D-xylo-pyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranosyl]- 28-O -[alpha-L-rhamnopyranosyl (1-->4)-beta-D-glucopyranosyl (1-->6) beta-D-glucopyranosyl]-hederagenin (N-IV), sucrose(N-V), beta-sitosterol(N-VI) and cyclolandenol(N-VII). Compounds N-I and N-II are new compounds, named nigeglanoside and nigeglanose, respectively. Apart from ten fatty acids in its oil have also been analysed. It is the first time for the study on chemical constituents of the seed of Nigella glandulifera.

摘要

从腺毛黑种草籽中分离出7种化合物。它们的结构被鉴定为山奈酚-3-O-β-D-吡喃半乳糖基(1→3)-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃葡萄糖苷(N-I)、2-O-[α-D-吡喃半乳糖基(1→4)-β-D-吡喃葡萄糖基]-β-D-呋喃果糖苷(N-II)、N,N-二甲基-1,2-二甲氧基-10,11-二氢阿朴啡氯化铵(N-III)、3-O-[β-D-吡喃木糖基(1→3)-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基]-28-O-[α-L-吡喃鼠李糖基(1→4)-β-D-吡喃葡萄糖基(1→6)β-D-吡喃葡萄糖基]-常春藤皂苷元(N-IV)、蔗糖(N-V)、β-谷甾醇(N-VI)和环羊毛甾醇(N-VII)。化合物N-I和N-II是新化合物,分别命名为腺毛黑种草苷和腺毛黑种草糖。此外,还分析了其油中的十种脂肪酸。这是首次对腺毛黑种草籽的化学成分进行研究。

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Evaluation on Anti-Inflammatory, Analgesic, Antitumor, and Antioxidant Potential of Total Saponins from Nigella glandulifera Seeds.
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