Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Korean J Anesthesiol. 2011 Nov;61(5):435-8. doi: 10.4097/kjae.2011.61.5.435. Epub 2011 Nov 23.
Indigo carmine has been used for eight decades with few adverse effects. Several of our patients, however, experienced severe hypotensive episodes after indigo carmine administration within a period of one month. Analysis of the raw materials used to formulate the preparation of indigo carmine we used showed that they contained impurities. Following recall of these impure materials, none of our patients experienced further hypotensive episodes.
靛胭脂已经使用了近 80 年，很少有不良反应。然而，在一个月的时间内，我们有几位患者在使用靛胭脂后出现严重的低血压发作。对我们使用的靛胭脂制剂原料进行分析后发现，它们含有杂质。在召回这些不纯的材料后，我们的患者没有再出现低血压发作。
