平卧大戟对角叉菜胶诱导的小鼠足垫水肿的局部抗炎作用。

Topical antiinflammatory effects of Euphorbia prostrata on carrageenan-induced footpad oedema in mice.

作者信息

Singla A K, Pathak K

机构信息

Department of Pharmaceutical Sciences, Panjab University, Chandigarh, India.

出版信息

J Ethnopharmacol. 1990 Jul;29(3):291-4. doi: 10.1016/0378-8741(90)90040-z.

DOI:10.1016/0378-8741(90)90040-z

PMID:2214815

Abstract

The ethyl acetate extract and a fraction, KSE-23, isolated chromatographically from the ethyl acetate extract of Euphorbia prostrata, showed significant antiinflammatory activity when topically applied in a murine model of carrageenan footpad oedema. KSE-23 was found to be more potent than indomethacin given in the same manner.

摘要

从平卧大戟乙酸乙酯提取物中通过色谱法分离得到的乙酸乙酯提取物和一个馏分KSE-23，在角叉菜胶致小鼠足跖水肿模型中局部应用时显示出显著的抗炎活性。发现KSE-23比以相同方式给药的吲哚美辛更有效。