Lynch Brian A, Fenta Yilma, Jacobson Robert M, Li Xujian, Juhn Young J
Division of Community Pediatric and Adolescent Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.
J Asthma. 2012 Feb;49(1):23-8. doi: 10.3109/02770903.2011.637596. Epub 2011 Dec 7.
To evaluate the effect of the timeliness of asthma diagnosis on chest X-ray (CXR) and antibiotic utilization in children.
This was a retrospective cohort study of 276 asthmatic children aged 5-12 years from Rochester, Minnesota. From the time when children met our predetermined asthma criteria, the frequency of CXR and antibiotic utilizations for respiratory illnesses were collected from medical records until age 18 years. Using a Poisson regression model, the frequency of CXR and antibiotic utilizations were compared in children with timely, delayed, or no clinician diagnosis of asthma.
Of the 276 asthmatic patients, 97 (35%) had a timely diagnosis, 122 (44%) had a delayed diagnosis, while 57 patients (21%) had no clinician diagnosis of asthma. There was no significant difference in CXR or antibiotic utilization for respiratory illness between these groups. In addition, this was true for the comparison between the timely diagnosed group and the delayed diagnosed group combining both the group with a delay in asthma diagnosis and the group who never had asthma diagnosis.
A delay in the diagnosis of asthma in children is common and overall it may not influence antibiotic and CXR utilization for respiratory symptoms by clinicians. However, its impact on access to asthma-related therapies and other healthcare utilizations could be possible and was not assessed in this study. Given the limitations of our study, a larger prospective study needs to be considered.
评估哮喘诊断及时性对儿童胸部X线(CXR)检查及抗生素使用情况的影响。
这是一项对来自明尼苏达州罗切斯特市的276名5至12岁哮喘儿童进行的回顾性队列研究。从儿童符合我们预先设定的哮喘标准之时起,收集其病历中直至18岁时因呼吸道疾病进行CXR检查及使用抗生素的频率。使用泊松回归模型,比较哮喘诊断及时、延迟或未获临床医生诊断的儿童的CXR检查及抗生素使用频率。
在276名哮喘患者中,97名(35%)诊断及时,122名(44%)诊断延迟,而57名患者(21%)未获临床医生诊断为哮喘。这些组之间在因呼吸道疾病进行CXR检查或使用抗生素方面无显著差异。此外,将哮喘诊断延迟组和从未被诊断为哮喘的组合并后,及时诊断组与延迟诊断组之间的比较也是如此。
儿童哮喘诊断延迟很常见,总体而言,这可能不会影响临床医生针对呼吸道症状进行的抗生素使用及CXR检查。然而,其对获得哮喘相关治疗及其他医疗保健利用的影响可能存在,本研究未对此进行评估。鉴于我们研究的局限性,需要考虑开展更大规模的前瞻性研究。