Upper Gastrointestinal Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Expert Rev Gastroenterol Hepatol. 2012 Feb;6(1):115-22. doi: 10.1586/egh.11.91.
Esophageal cancer is an aggressive and physically and emotionally devastating disease. It has one of the poorest survival rates among all malignant tumors, mainly due to late symptom presentation and early metastatic dissemination. Cure is possible through extensive surgery, typically followed by a long recovery period, affecting general well-being, as well as basic aspects of life, such as eating, drinking and socializing. Health-related quality of life (HRQL) is a multidimensional concept assessing symptoms and functions related to a disease or its treatment from the patient's perspective. HRQL is a fundamental part of treatment in surgical oncology, particularly in esophageal cancer. This review assesses the scientific data regarding some HRQL aspects after esophageal cancer surgery, for example, postoperative recovery time, determinants of postoperative HRQL and long-term HRQL.
食管癌是一种侵袭性强的疾病,会给患者带来身体和精神上的双重打击。它是所有恶性肿瘤中生存率最低的肿瘤之一,主要原因是其症状出现较晚,且早期转移扩散。通过广泛的手术可以实现治愈,但通常需要长期的恢复期,这会影响患者的整体健康状况以及饮食、饮水和社交等基本生活方面。健康相关生活质量(HRQL)是一个多维概念,从患者的角度评估与疾病或其治疗相关的症状和功能。HRQL 是外科肿瘤学治疗的一个基本组成部分,特别是在食管癌中。本综述评估了食管癌手术后一些 HRQL 方面的科学数据,例如术后恢复时间、术后 HRQL 的决定因素和长期 HRQL。