International Graduate School of Neuroscience, Ruhr-University Bochum, Germany.
Expert Rev Neurother. 2012 Jan;12(1):71-81. doi: 10.1586/ern.11.183.
Therapeutic strategies for improving social cognition in patients with schizophrenia have shown much promise in improving social functioning, as well as remediating core psychotic symptoms. However, the efficacy of previous interventions has often been limited by the ambiguity and inconsistency of the categorized subdomains of social cognition, including theory of mind, emotion processing, social perception and attributional bias. Recent research in social and cognitive neuroscience has revealed many new issues that could contribute to the development of more integrated approaches for improving social functioning. The application of such neuroscientific work to a therapeutic and diagnostic context is likely to encourage more effective transference of learned skills to real-world social functioning. This article seeks to provide a comprehensive review of previous social cognitive interventions for schizophrenia, highlight some crucial limitations of these and present the relevance of recent advances in neuroscientific research in possible future treatment strategies. It is emphasized that a more integrated and naturalistic approach for improving social functioning with greater sensitivity for neuroscientific findings related to the psychopathology of schizophrenia is warranted.
改善精神分裂症患者社会认知的治疗策略在改善社会功能以及矫正核心精神病症状方面显示出很大的前景。然而，之前干预措施的效果往往受到社会认知分类子领域的模糊性和不一致性的限制，这些子领域包括心理理论、情绪处理、社会知觉和归因偏差。最近的社会和认知神经科学研究揭示了许多新问题，这些问题可能有助于开发更综合的方法来改善社会功能。将这些神经科学工作应用于治疗和诊断环境中，可能会鼓励将所学技能更有效地转移到现实世界的社会功能中。本文旨在全面回顾精神分裂症的先前社会认知干预措施，强调这些干预措施的一些关键局限性，并介绍神经科学研究的最新进展在可能的未来治疗策略中的相关性。文中强调，需要采用更综合和自然的方法来改善社会功能，并对与精神分裂症病理学相关的神经科学发现更敏感。
