Department of Medical Physics, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan S7N 4H4, Canada.
Med Phys. 2011 Dec;38(12):6592-602. doi: 10.1118/1.3658572.
The goal of this work was to implement a recently proposed small field dosimetry formalism [Alfonso et al., Med. Phys. 35(12), 5179-5186 (2008)] for a comprehensive set of diode detectors and provide the required Monte Carlo generated factors to correct measurement.
Jaw collimated square small field sizes of side 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, and 3.0 cm normalized to a reference field of 5.0 cm × 5.0 cm were used throughout this study. Initial linac modeling was performed with electron source parameters at 6.0, 6.1, and 6.2 MeV with the Gaussian FWHM decreased in steps of 0.010 cm from 0.150 to 0.100 cm. DOSRZnrc was used to develop models of the IBA stereotactic field diode (SFD) as well as the PTW T60008, T60012, T60016, and T60017 field diodes. Simulations were run and isocentric, detector specific, output ratios (OR(det)) calculated at depths of 1.5, 5.0, and 10.0 cm. This was performed using the following source parameter subset: 6.1 and 6.2 MeV with a FWHM = 0.100, 0.110, and 0.120 cm. The source parameters were finalized by comparing experimental detector specific output ratios with simulation. Simulations were then run with the active volume and surrounding materials set to water and the replacement correction factors calculated according to the newly proposed formalism.
In all cases, the experimental field size widths (at the 50% level) were found to be smaller than the nominal, and therefore, the simulated field sizes were adjusted accordingly. At a FWHM = 0.150 cm simulation produced penumbral widths that were too broad. The fit improved as the FWHM was decreased, yet for all but the smallest field size worsened again at a FWHM = 0.100 cm. The simulated OR(det) were found to be greater than, equivalent to and less than experiment for spot size FWHM = 0.100, 0.110, and 0.120 cm, respectively. This is due to the change in source occlusion as a function of FWHM and field size. The corrections required for the 0.5 cm field size were 0.95 (± 1.0%) for the SFD, T60012 and T60017 diodes and 0.90 (± 1.0%) for the T60008 and T60016 diodes-indicating measured output ratios to be 5% and 10% high, respectively. Our results also revealed the correction factors to be the same within statistical variation at all depths considered.
A number of general conclusions are evident: (1) small field OR(det) are very sensitive to the simulated source parameters, and therefore, rigorous Monte Carlo linac model commissioning, with respect to measurement, must be pursued prior to use, (2) backscattered dose to the monitor chamber should be included in simulated OR(det) calculations, (3) the corrections required for diode detectors are design dependent and therefore detailed detector modeling is required, and (4) the reported detector specific correction factors may be applied to experimental small field OR(det) consistent with those presented here.
本工作旨在实现最近提出的小射野剂量学公式[Alfonso 等人,医学物理 35(12),5179-5186(2008)],用于一整套二极管探测器,并提供所需的蒙特卡罗生成因子来校正测量。
本研究使用了归一化为参考场 5.0 cm×5.0 cm 的 0.5、0.6、0.7、0.8、0.9、1.0 和 3.0 cm 边长的方形射野。最初的直线加速器建模使用电子源参数在 6.0、6.1 和 6.2 MeV 下进行,高斯 FWHM 从 0.150 逐渐减小到 0.100 cm,步长为 0.010 cm。DOSRZnrc 用于开发 IBA 立体定向场二极管(SFD)以及 PTW T60008、T60012、T60016 和 T60017 场二极管的模型。进行了模拟,并在 1.5、5.0 和 10.0 cm 深度处计算了等中心、探测器特定的输出比(OR(det))。这是通过以下源参数子集完成的:6.1 和 6.2 MeV,FWHM=0.100、0.110 和 0.120 cm。通过将实验探测器特定输出比与模拟进行比较来确定源参数。然后使用设定为水的有源体积和周围材料进行模拟,并根据新提出的公式计算替换校正因子。
在所有情况下,实验射野宽度(在 50%水平)都发现小于标称值,因此相应地调整了模拟射野尺寸。在 FWHM=0.150 cm 的情况下,模拟产生的半影宽度太宽。随着 FWHM 的减小,拟合情况得到改善,但除了最小射野尺寸外,在 FWHM=0.100 cm 时再次恶化。对于 FWHM=0.100、0.110 和 0.120 cm 的光斑尺寸,模拟的 OR(det)分别大于、等于和小于实验值。这是由于源遮挡随 FWHM 和射野尺寸而变化。对于 0.5 cm 射野尺寸,SFD、T60012 和 T60017 二极管的校正因子为 0.95(±1.0%),T60008 和 T60016 二极管的校正因子为 0.90(±1.0%),这表明测量的输出比分别高 5%和 10%。我们的结果还表明,在考虑的所有深度内,校正因子在统计上是相同的。
有几个一般性结论是明显的:(1)小射野 OR(det)对模拟源参数非常敏感,因此,在使用之前必须进行严格的基于测量的蒙特卡罗直线加速器调试;(2)应在模拟 OR(det)计算中包含监测室的反向散射剂量;(3)二极管探测器所需的校正因子取决于设计,因此需要进行详细的探测器建模;(4)报告的探测器特定校正因子可应用于与这里提出的一致的实验小射野 OR(det)。