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BACKGROUND & PURPOSE: Investigate the applicability of a series of detectors in small field dosimetry and the possible differences between their responses to FF and FFF beams. This work extends upon the series of detectors used by other authors to also include metal-oxide-semiconductor field-effect transistors (MOSFETs) detectors and radiochromic film. We also included a later correction of output factors (OFs) recommended by the recently published IAEA´s code of practice TRS 483 on dosimetry of small static fields used in external beam radiotherapy.
MATERIALS & METHODS: The OFs, profiles, and PDDs of 6 MV and 6 MV FFF beams were measured with 11 different detectors using field sizes between 0.6 × 0.6 cm2 and 10 × 10 cm2.
RESULTS: The OFs of the FFF beams were lower than those of the FF beams for field sizes larger than 3 × 3 cm2 but higher for field sizes smaller than 3 × 3 cm2. After applying the IAEA´s TRS 483 corrections, the final OFs were compatible with our initial results when considering uncertainties involved. Small-volume detectors are preferable for measuring the penumbra of these small fields where this attribute is higher in the crossline direction than in the inline direction. The R100 of equivalent-quality FFF beams was higher compared to the corresponding flattened beams.
CONCLUSIONS: We observed no difference for the dose responses between 6 MV and 6 MV FFF beams for any of the detectors. OF results, profiles and PDDs were clearly consistent with the previously published literature regarding the Versa HD linac. Correcting our first OFs, taken as ratio of detector charges, with the IAEA´s TRS 483 corrections to obtain the final OFs, did not make the former significantly different.

BACKGROUND & PURPOSE: Investigate the applicability of a series of detectors in small field dosimetry and the possible differences between their responses to FF and FFF beams. This work extends upon the series of detectors used by other authors to also include metal-oxide-semiconductor field-effect transistors (MOSFETs) detectors and radiochromic film. We also included a later correction of output factors (OFs) recommended by the recently published IAEA´s code of practice TRS 483 on dosimetry of small static fields used in external beam radiotherapy.
MATERIALS & METHODS: The OFs, profiles, and PDDs of 6 MV and 6 MV FFF beams were measured with 11 different detectors using field sizes between 0.6 × 0.6 cm2 and 10 × 10 cm2.
RESULTS: The OFs of the FFF beams were lower than those of the FF beams for field sizes larger than 3 × 3 cm2 but higher for field sizes smaller than 3 × 3 cm2. After applying the IAEA´s TRS 483 corrections, the final OFs were compatible with our initial results when considering uncertainties involved. Small-volume detectors are preferable for measuring the penumbra of these small fields where this attribute is higher in the crossline direction than in the inline direction. The R100 of equivalent-quality FFF beams was higher compared to the corresponding flattened beams.
CONCLUSIONS: We observed no difference for the dose responses between 6 MV and 6 MV FFF beams for any of the detectors. OF results, profiles and PDDs were clearly consistent with the previously published literature regarding the Versa HD linac. Correcting our first OFs, taken as ratio of detector charges, with the IAEA´s TRS 483 corrections to obtain the final OFs, did not make the former significantly different.

背景与目的：研究一系列探测器在小野剂量学中的适用性，以及它们对均整和兆伏级快速千伏（FFF）射线响应的可能差异。本工作扩展了其他作者使用的一系列探测器，还包括金属氧化物半导体场效应晶体管（MOSFET）探测器和光致变色胶片。我们还包括了最近发布的国际原子能机构（IAEA）实践技术报告 TRS 483 中建议的输出因子（OFs）的后期修正，该报告涉及外照射放射治疗中小静态野剂量学。
材料与方法：使用 11 种不同的探测器，在 0.6×0.6cm2 至 10×10cm2 的射野尺寸下，测量了 6MV 和 6MVFFF 射线的 OFs、剂量分布曲线和百分深度剂量（PDD）。
结果：对于大于 3×3cm2 的射野尺寸，FFF 射线的 OFs 低于均整射线，但对于小于 3×3cm2 的射野尺寸，FFF 射线的 OFs 高于均整射线。应用 IAEA 的 TRS 483 修正后，考虑到所涉及的不确定性，最终的 OFs 与我们的初始结果一致。对于这些小射野的半影测量，小体积探测器更可取，因为在横连线方向上，该属性高于在纵连线方向上。与相应的平坦化射线相比，等效质量的 FFF 射线的 R100 更高。
结论：对于任何探测器，我们都没有观察到 6MV 和 6MVFFF 射线之间的剂量响应有差异。OF 结果、剂量分布曲线和 PDD 与之前关于 Versa HD 直线加速器的文献明显一致。用 IAEA 的 TRS 483 修正来修正我们最初的作为探测器电荷量比的 OFs，以获得最终的 OFs，并没有使前者显著不同。