Clinic of Obstetrics and Gynecology, Vilnius University Faculty of Medicine, Lithuania.
Acta Obstet Gynecol Scand. 2012 Apr;91(4):511-3. doi: 10.1111/j.1600-0412.2011.01334.x. Epub 2012 Jan 26.
We determined the risk of high-risk human papillomavirus (HR-HPV) infection in 169 15- to 22-year-old sexually active Lithuanian women attending two outpatient clinics in Vilnius. The Digene(®) Hybrid Capture II DNA test was used to test for HR-HPV infection on material collected by cervical swabs. The findings were compared with the pattern of sexual behavior as given in questionnaire replies. The overall risk of HR-HPV was 23.1%, but 60.0% in adolescents ≤15 years old. Mean age at first intercourse was 17.1 years; 73.5% of women had only had one sexual partner and 24.5% more than one. The risk of HR-HPV was higher in women with more than one sexual partner, and related to being a smoker and to early age at the first intercourse. Our results confirm that smoking, early coitarche, multiple sexual partners and unprotected vaginal intercourse are related to the risk of HR-HPV infection in young women.
我们在维尔纽斯的两家门诊诊所，对 169 名 15 至 22 岁有性行为的立陶宛活跃女性进行了高危型人乳头瘤病毒（HR-HPV）感染风险评估。我们采用 Digene(®) Hybrid Capture II DNA 检测法，通过宫颈拭子采集的样本，对 HR-HPV 感染进行检测。检测结果与问卷调查中报告的性行为模式进行了比较。总体 HR-HPV 感染风险为 23.1%，但 15 岁及以下青少年的感染风险为 60.0%。初次性行为的平均年龄为 17.1 岁；73.5%的女性只有一个性伴侣，24.5%的女性有多个性伴侣。性伴侣多于一个的女性 HR-HPV 感染风险更高，且与吸烟、初次性行为年龄早有关。我们的研究结果证实，吸烟、初次性行为年龄早、性伴侣多、无保护阴道性交与年轻女性 HR-HPV 感染风险相关。
